Transglutaminase-2 (TGM2) antibody

Principal name

Transglutaminase-2 (TGM2) antibody

Alternative names for Transglutaminase-2 (TGM2) antibody

TGase C, TGase-H, Tissue transglutaminase, Protein-glutamine gamma-glutamyltransferase 2

SwissProt ID

P21980 (Human), P21980-2, P21981 (Mouse), P51176 (Bovin), Q01841 (Chick)

Gene ID

7052 (TGM2), 21817 (Tgm2)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Chk (Chicken), Rt (Rat), Ze (Zebrafish), GP (Guinea Pig), Por (Porcine), Mky (Monkey), Can (Canine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Transglutaminase-2 (TGM2) antibody

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, TGM2 is the autoantigen implicated in celiac disease.Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.

General readings

Barone M.V. et al. Humoral Immune Response to Tissue Transglutaminase Is Related to Epithelial Cell Proliferation in Celiac Disease. Gastroenterology. April 2007,Volume 132, Issue 4, Pages 1245-1253 .

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Transglutaminase-2 (TGM2) (578-591) antibody

  Goat Polyclonal Antibody against Transglutaminase 2 (aa578-591)  
TA309513 (1µg/ml) staining of Mouse Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Hu, Ms, Por, Rt E, WB
0.1 mg / €360.00
  OriGene Technologies, Inc.

Transglutaminase-2 (TGM2) antibody

  Anti-TGM2 Rabbit Polyclonal Antibody  
Predicted band size: 77 kDa . Positive control: Lovo and hela cell, human liver cancer and fetal liver tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lane1: Lovo cell lysate Lane2: Hela cell lysate Lane3: Human liver cancer tissue lysate Lane4:Human fetal liver tissue lysate Lysate: 50 ug per lane Primary antibody: 1/150 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Transglutaminase-2 (TGM2) antibody

  Anti-TGM2 Rabbit Polyclonal Antibody  
Predicted band size: 77 kDa . Positive control: Lovo and hela cell, human liver cancer tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lane1: Lovo lysate Lane2: Hela cell lysate Lane3: Human liver cancer tissue lysate Lysates: 50 ug per lane Primary antibody: 1/150 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Transglutaminase-2 (TGM2) (C-term) antibody

  Goat Anti-TGM2 Antibody  
TA326310 (0.05µg/ml) staining of Human Pancreas cancer lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, WB
0.1 mg / €360.00
  OriGene Technologies, Inc.

Transglutaminase-2 (TGM2) antibody

  Rabbit anti-TGM2 Polyclonal Antibody  
Western blot analysis of extracts of Hela cell and HepG2 cell lysate using TGM2 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

Transglutaminase-2 (TGM2) antibody

Placenta: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt IP, P, WB
50 µl / €380.00
  OriGene Technologies GmbH

Transglutaminase-2 (TGM2) antibody

Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) using Transglutaminase-2 antibody. Rabbit IgG Purified Hu, Ms, Rt IP, P, WB
50 µl / €380.00
  OriGene Technologies GmbH

Transglutaminase-2 (TGM2) (full length) antibody

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu, Ms, Rt IP, P, WB
50 µg / €380.00
  OriGene Technologies GmbH

Transglutaminase-2 (TGM2) antibody

Human liver stained in immunohisto-chemistry with transgluaminase 2 antibody Rabbit Serum GP, Hu, Ms, Por, Rt C, E, WB
0.2 ml / €400.00
  OriGene Technologies GmbH

9 Item(s)

per page
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