TRAT1 / TRIM antibody

Principal name

TRAT1 / TRIM antibody

Alternative names for TRAT1 / TRIM antibody

TCRIM, T-cell receptor-associated transmembrane adapter 1, T-cell receptor-interacting molecule

SwissProt ID

Q3SYX1 (Bovin), Q3UU67 (Mouse), Q6PIZ9 (Human)

Gene ID

50852 (TRAT1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Flow Cytometry (F), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of TRAT1 / TRIM antibody

TRIM (TCR-Interactin molecule) stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells. Sequence analysis predicts that TRIM is a 186-amino acid type III transmembrane protein containing an 8-amino acid extracellular domain, which includes a cys residue, and a 19-amino acid transmembrane region that lacks charged residues. The intracellular portion possesses 4 potential phosphorylation sites and 8 tyrosine residues. It is strongly expressed in adult thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level). It can be found in the foetal thymus at weeks 17-24 of gestation but is undetectable in bone marrow and foetal liver.

General readings

This product has been used in:Kirchgessner H et al. The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain. J Exp Med 193:1269-84 (2001). PubMed PMID: 11390434
Huynh T et al. Developmentally regulated expression of the transmembrane adaptor protein trim in fetal and adult T cells. Scand J Immunol 54:146-54 (2001). PubMed PMID: 11439161

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TRAT1 / TRIM (29-186) antibody

Western blot of human Jurkat T cell line lysate (1% laurylmaltoside); non-reduced sample, immunostained by  mAb TRIM-04 and goat anti-mouse IgG (H+L)-HRP conjugate. Mouse IgG2a TRIM-04 Purified Hu F, IP, WB
0.1 mg / €240.00
  Acris Antibodies GmbH

TRAT1 / TRIM (29-186) antibody

Western blot of human Jurkat T cell line lysate (1% laurylmaltoside); non-reduced sample, immunostained by  mAb TRIM-04 and goat anti-mouse IgG (H+L)-HRP conjugate. Mouse IgG2a TRIM-04 PE Hu F
0.1 mg / €370.00
  Acris Antibodies GmbH

TRAT1 / TRIM antibody

TRAT1 / TRIM Mouse IgG2a TRIM-04 Hu F, IP, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

TRAT1 / TRIM antibody

TRAT1 / TRIM Mouse IgG2a TRIM-04 Hu F, IP, WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

TRAT1 / TRIM antibody

TRAT1 / TRIM Mouse IgG2a TRIM-04 Aff - Purified Hu F, IP, WB
0.1 mg / €340.00
  Novus Biologicals Inc.

TRAT1 / TRIM antibody

Immunohistochemistry-Paraffin: XRN2 Antibody [NBP1-89660] - Immunohistochemistry-Paraffin: XRN2 Antibody [NBP1-89660] Immunohistochemical staining of human tonsil shows cytoplasmic positivity in lymphoid cells outside the reaction centra. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TRAT1 / TRIM

TRAT1 / TRIM Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

TRAT1 overexpression lysate

TRAT1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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