Trefoil factor 3 / ITF antibody

Principal name

Trefoil factor 3 / ITF antibody

Alternative names for Trefoil factor 3 / ITF antibody

TFF3, Intestinal trefoil factor, TFI, Polypeptide P1.B

SwissProt ID

Q96NX0 (Human)

Gene ID

7033 (TFF3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Trefoil factor 3 / ITF antibody

Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. Trefoil peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain and clustered in human chromosome 21q22.3. Trefoil Factor 3 (TFF3) is one of three trefoil peptides secreted by epithelial cells that line mucus membranes in the large and small intestines and lower respiratory tract. TFF3 is mainly active as a disulfide-linked homodimer and may have a role in promoting cell migration in healing processes. It is involved in the maintenance and repair of the intestinal mucosa.

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