TREML2 antibody

Principal name

TREML2 antibody

Alternative names for TREML2 antibody

C6orf76, TLT2, TLT-2, Trem-like transcript 2 protein, Triggering receptor expressed on myeloid cells-like protein 2

SwissProt ID

Q2LA85 (Mouse), Q5T2D2 (Human)

Gene ID

79865 (TREML2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of TREML2 antibody

TREML2 is expressed throughout B cell development in addition to being expressed on macrophages and neutrophils and is the only TREM molecule to be found on lymphocytes. TREML2 is expressed on B lineage cells early in development, and the highest level of expression is detected on those mature peripheral B cell subpopulations that are involved in the initial humoral immune response against bacterial pathogens. TREML2 is unique in that it lacks either the conserved transmembrane lysine residue or ITAM/ITIMs within its own cytoplasmic domain. Thus, TREML2 does not exhibit any of the features associated with classical tyrosine-based signaling. Monocytes in the bone marrow or peripheral blood do not express detectable levels of TREML2, but its expression is up-regulated in conjunction with differentiation into macrophages. TREML2 is present on neutrophils in the bone marrow as well as the periphery, and inflammatory stimuli result in a dramatic increase in the expression of TREML2 on these cells in vivo.TREML2 is a single-pass type I membrane protein, and it contains 1 Ig-like V-type (immunoglobulin-like) domain. It is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 and TREM2, but it has distinct structural and functional properties.

General readings

King,R.G., (2006) J. Immunol. 176 (10), 6012-6021

6 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TREML2 antibody

WB Suggested Anti-TREML2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

TREML2 antibody

WB Suggested Anti-TREML2 Antibody Titration: 0.2-1 ug/ml; Positive Control: 721_B cell lysate TREML2 is supported by BioGPS gene expression data to be expressed in 721_B Rabbit IgG Purified Can, Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

TREML2 (N-term) antibody

TREML2 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

TREML2 antibody

Human 721_B; WB Suggested Anti-TREML2 Antibody Titration: 0.2-1 ug/ml. Positive Control: 721_B cell lysate. TREML2 is supported by BioGPS gene expression data to be expressed in 721_B.; TREML2 antibody - middle region (ARP49878_P050) in Human 721_B cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TREML2

TREML2 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

TREML2 overexpression lysate

TREML2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

6 Item(s)

per page
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