TREX1 antibody

Principal name

TREX1 antibody

Alternative names for TREX1 antibody

DNase III, 3'-5' exonuclease TREX1, Three prime repair exonuclease 1

SwissProt ID

Q91XB0 (Mouse), Q9BG99 (Bovin), Q9NSU2 (Human)

Gene ID

11277 (TREX1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of TREX1 antibody

Trex1 (ATRIP) is the major human 3' to 5' exonuclease which is required for checkpoint signaling after DNA damage. It is ubiquitously expressed, binds to single stranded DNA coated with replication protein A that accumulates at sites of DNA damage and recruits the ataxia telangiectasia and Rad3 related protein (ATR), a checkpoint kinase, to sites of DNA damage and replication stress. Trex1 is required for ATR expression. This gene uses two different open reading frames. The upstream ORF encodes proteins which interact with ATR and localize to intranuclear foci induced by DNA damage and are essential components of the DNA damage checkpoint. The downstream ORF encodes proteins with 3' to 5' exonuclease activity and may be a subunit of human DNA polymerase III. Multiple transcript variants encoding different isoforms have been found. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. TREX1 antibody will not cross-react with the related protein TREX2.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TREX1 antibody

Western Blot: TREX1 Antibody [TA337178] - WB analysis of TREX1 partial recombinant protein by using TREX1 antibody at a concentration of 1ug/ml. Rabbit Purified Hu C, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TREX1 antibody

Western blot analysis of TREX1 in human spleen tissue lysate with TREX1 antibody at (A) 0.5 ug/ml and (B) 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TREX1 Control Peptide

TREX1
50 µg / €160.00
  Acris Antibodies GmbH

TREX1 antibody

TREX1 Mouse Serum Hu E
50 µl / €290.00
  Abnova Taiwan Corp.

TREX1 antibody

Western Blot analysis of TREX1 expression in transfected 293T cell line (H00011277-T01) by TREX1 MaxPab polyclonal antibody.

Lane 1: TREX1 transfected lysate(33.44 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

TREX1 antibody

Western Blot analysis of TREX1 expression in transfected 293T cell line (H00011277-T02) by TREX1 MaxPab polyclonal antibody.

Lane 1: TREX1 transfected lysate(40.59 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

TREX1 antibody

Western Blot analysis of TREX1 expression in transfected 293T cell line (H00011277-T02) by TREX1 MaxPab polyclonal antibody.

Lane 1: TREX1 transfected lysate(40.59 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

TREX1 antibody

TREX1 MaxPab rabbit polyclonal antibody. Western Blot analysis of TREX1 expression in mouse spleen. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

TREX1 antibody

TREX1 MaxPab rabbit polyclonal antibody. Western Blot analysis of TREX1 expression in human pancreas. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

TREX1 antibody

TREX1 Mouse IgG2b 2F10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

TREX1 antibody

TREX1 Mouse IgG2a 1B1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

TREX1 antibody

Immunohistochemistry-Paraffin: TREX1 Antibody [NBP1-76977] - Human spleen tissue with TREX1 antibody at 2.5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

TREX1 antibody

Immunohistochemistry-Paraffin: TREX1 Antibody [NBP1-89202] - Immunohistochemical staining of human colon shows moderate nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TREX1

TREX1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TREX1

TREX1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

TREX1

TREX1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TREX1

TREX1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

TREX1 293T Cell Transient Overexpression Lysate(Denatured)

TREX1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

TREX1 293T Cell Transient Overexpression Lysate(Denatured)

TREX1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

TREX1 overexpression lysate

TREX1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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