TREX1 antibody

Principal name

TREX1 antibody

Alternative names for TREX1 antibody

DNase III, 3'-5' exonuclease TREX1, Three prime repair exonuclease 1

SwissProt ID

Q91XB0 (Mouse), Q9BG99 (Bovin), Q9NSU2 (Human)

Gene ID

11277 (TREX1), 22040 (Trex1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Frozen Sections (C)

Background of TREX1 antibody

Trex1 is the major human 3' to 5' exonuclease which is required for checkpoint sigling after D damage. It is ubiquitously expressed, binds to single stranded D coated with replication protein A that accumulates at sites of D damage and recruits the ataxia telangiectasia and Rad3 related protein (ATR), a checkpoint kise, to sites of D damage and replication stress. Trex1 is required for ATR expression. This gene uses two different open reading frames. The upstream ORF encodes proteins which interact with ATR and localize to intranuclear foci induced by D damage and are essential components of the D damage checkpoint. The downstream ORF encodes proteins with 3' to 5' exonuclease activity and may be a subunit of human D polymerase III. Multiple transcript variants encoding different isoforms have been found. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. TREX1 antibody will not cross-react with the related protein TREX2.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TREX1 antibody

  Rabbit Polyclonal TREX1 Antibody  
Western Blot: TREX1 Antibody [TA337178] - WB analysis of TREX1 partial recombinant protein by using TREX1 antibody at a concentration of 1ug/ml. Rabbit Purified Hu C, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TREX1 antibody

  Rabbit Polyclonal TREX1 Antibody  
Western blot analysis of TREX1 in human spleen tissue lysate with TREX1 antibody at (A) 0.5 ug/ml and (B) 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

TREX1 - human gene knockout kit via CRISPR

TREX1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

TREX1 - human gene knockout kit via CRISPR

TREX1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

TREX1 - human gene knockout kit via CRISPR

TREX1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

TREX1 - human gene knockout kit via CRISPR

TREX1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Trex1 - mouse gene knockout kit via CRISPR

Trex1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Trex1 - mouse gene knockout kit via CRISPR

Trex1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Trex1 - mouse gene knockout kit via CRISPR

Trex1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Trex1 - mouse gene knockout kit via CRISPR

Trex1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

TREX1 overexpression lysate

TREX1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TREX1 (mGFP-tagged) - Human three prime repair exonuclease 1 (TREX1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, TREX1 (mGFP-tagged) - Human three prime repair exonuclease 1 (TREX1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €950.00
  OriGene Technologies, Inc.

Lenti ORF particles, TREX1 (Myc-DDK tagged) - Human three prime repair exonuclease 1 (TREX1), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, TREX1 (Myc-DDK tagged) - Human three prime repair exonuclease 1 (TREX1), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €850.00
  OriGene Technologies, Inc.

13 Item(s)

per page
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