TREX2 antibody

Principal name

TREX2 antibody

Alternative names for TREX2 antibody

3'-5' exonuclease TREX2, Three prime repair exonuclease 2

SwissProt ID

Q9BQ50 (Human), Q9R1A9 (Mouse)

Gene ID

11219 (TREX2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Rabbit, Mouse

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of TREX2 antibody

TREX2 is one of two major human 3' to 5' exonucleases which are required for checkpoint signaling after DNA damage. While the related protein TREX1 is required for ATR expression and mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis, less is known about TREX2. Like TREX1, TREX2 is ubiquitously expressed in all tissues examined. X-ray crystallography studies of TREX2-single strand DNA complexes revealed that TREX2 binds DNA as a dimer and may act to displace the second DNA strand, suggesting that TREX2 unzips and denatures double stranded DNA and feed the substrate DNA strand into the TREX2 active site. At least two isoforms of TREX2 are known to exist. This TREX2 antibody will not cross-react with the related protein TREX1.

General readings

Parra D., et al. (2009) Cancer Res. 69(16):6676-84.
Perrino FW., et al. (2008) J Biol Chem. 283(31):21441-52.

13 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TREX2 antibody

Western blot analysis of TREX2 in rat liver tissue lysate with TREX2 antibody at 2.5 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TREX2 Control Peptide

TREX2
50 µg / €160.00
  Acris Antibodies GmbH

TREX2 antibody

TREX2 antibody Cat.-No AP31979PU-N staining of paraffin embedded Human Breast at 3.8 μg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat Aff - Purified Hu E, P
0.1 mg / €340.00
  Acris Antibodies GmbH

TREX2 antibody

TREX2 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

TREX2 antibody

TREX2 Goat IgG Hu E, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

TREX2 antibody

Immunohistochemistry-Paraffin: TREX2 Antibody [NBP1-76978] - Human liver tissue with TREX2 antibody at 2.5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TREX2

TREX2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

TREX2 (1-236, His-tag)

TREX2 Human Purified > 95 % E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

TREX2 (1-236, His-tag)

TREX2 Human Purified > 95 % E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

TREX2

TREX2 Human
0.1 mg / €380.00
  Abnova Taiwan Corp.

TREX2

TREX2 Human Purified
0.1 mg / €380.00
  Novus Biologicals Inc.

TREX2

TREX2 Human Purified
0.5 mg / €870.00
  Novus Biologicals Inc.

Lysates (Overexpressed)

Catalog No.    

TREX2 overexpression lysate

TREX2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

13 Item(s)

per page
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