TRIM30A antibody

Principal name

TRIM30A antibody

Alternative names for TRIM30A antibody

Rpt-1, Rpt1, Trim30, Tripartite motif-containing protein 30A, Down regulatory protein of interleukin-2 receptor, Tripartite motif-containing protein 30

SwissProt ID

P15533

Gene ID

20128 (Trim30a), 434219

Available reactivities

Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of TRIM30A antibody

TRIM30 belongs to a family of the tripartite motif (TRIM) proteins involved in the regulation of cell proliferation, differentiation, development, oncogenesis, apoptosis and antiviral responses. The TRIM protein family is an expanding family of RING (\'really interesting new gene\') proteins, also known as RBCC proteins as they contain an RBCC motif, which comprises a RING domain, one or two B-boxes and a predicted coiled-coil region. Studies have shown that some TRIM family members are critical to innate immunity; TRIM5, TRIM19 and TRIM25, for example, have been shown to restrict viral infection. A recent study shows that TRIM30 functions as a negative modulator of the TLR signaling pathway, by targeting TAB2 and TAB3, and contributes to the inhibition of TLR-mediated NFkappa-B activation. The importance of TRIM30 in the attenuation or termination of NFkappa-B activation suggests that targeting of TAB2 and TAB3 by TRIM30 alpha may be a mechanism for modulating many types of immune responses.

2 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TRIM30A Control Peptide

TRIM30A
50 µg / €160.00
  Acris Antibodies GmbH

TRIM30A Control Peptide

TRIM30A
50 µg / €160.00
  Acris Antibodies GmbH

2 Item(s)

per page
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