Triosephosphate isomerase (TPI1) antibody

Principal name

Triosephosphate isomerase (TPI1) antibody

Alternative names for Triosephosphate isomerase (TPI1) antibody

Triose-phosphate isomerase, TPI, TIM

SwissProt ID

P00939 (Rabit), P00940 (Chick), P00942 (Yeast), P17751 (Mouse), P48500 (Rat), P54714 (Canfa), P60174 (Human), Q29371 (Pig), Q5E956 (Bovin)

Gene ID

7167 (TPI1), 851620, 21991 (Tpi1), 24849

Available reactivities

Bt (Bat), Bov (Bovine), Can (Canine), Chk (Chicken), Dros (Drosophila), Eq (Equine), Fi (Fish), Fu (Fungi), Hst (Hamster), Hu (Human), Mky (Monkey), Ms (Mouse), Por (Porcine), Prim (Primate), Rb (Rabbit), Rt (Rat), Xen (Xenopus), Bear, Bakers Yeast, GP (Guinea Pig)

Available hosts

Goat, Rabbit, Sheep, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Dot blot (Dot), Immunodiffusion (ID), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Radioimmunoassay (R)

Background of Triosephosphate isomerase (TPI1) antibody

Triosephosphate isomerase (TIM) catalyses the reversible interconversion of G3P and DHAP. Only G3P can be used in glycolysis, therefore TIM is essential for energy production, allowing two molecules of G3P to be produced for every glucose molecule, thereby doubling the energy yield. Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) [MIM:190450]. TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection.

General readings

1. O'Connell K, Gannon J, Doran P, Ohlendieck K.
Proteomic profiling reveals a severely perturbed protein expression pattern in aged skeletal muscle. Med. 2007 Aug;20(2):145-53. PMID: 17611631
2. Kim JE, Koo KH, Kim YH, Sohn J, Park YG.
Identification of potential lung cancer biomarkers using an in vitro carcinogenesis model.
Exp Mol Med. 2008 Dec 31;40(6):709-20. PMID: 19116456
3. Jorge I, Navarro P, Martínez-Acedo P, Núñez E, Serrano H, Alfranca A, Redondo JM, Vázquez J.
Statistical model to analyze quantitative proteomics data obtained by 18O/16O labeling and linear ion trap mass spectrometry: application to the study of vascular endothelial growth factor-induced angiogenesis in endothelial cells.
Mol Cell Proteomics. 2009 May;8(5):1130-49.
PMID: 19181660
4. Honoré B, Buus S, Claësson MH. Identification of differentially expressed proteins in spontaneous thymic lymphomas from knockout mice with deletion of p53. Proteome Sci. 2008 Jun 10;6:18. PMID: 18544163
5. Vorum H, Østergaard M, Rice GE, Honoré B, Bek T. Identification of differentially regulated proteins in a patient with Leber's Congenital Amaurosis--a proteomic study. Proteome Sci. 2007 Feb 27;5:5. PMID: 17326818

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Triosephosphate isomerase (TPI1) antibody

  Rabbit Polyclonal antibody to Triosephosphate isomerase (triosephosphate isomerase 1)  
Triosephosphate isomerase antibody [C2C3], C-term detects TPI1 protein by Western blot analysis. A. 30 ug Neuro2A whole cell lysate/extract. B. 30 ug GL261 whole cell lysate/extract. C. 30 ug C8D30 whole cell lysate/extract. D. 30 ug NIH-3T3 whole cell ly Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €415.00
  OriGene Technologies, Inc.

Triosephosphate isomerase (TPI1) (C-term) antibody

  Goat Polyclonal Antibody against TPI1  
TA302993 staining (0.003µg/ml) of human liver lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, P, WB
0.1 mg / €360.00
  OriGene Technologies, Inc.

Triosephosphate isomerase (TPI1) (274-286) antibody

Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Bov, Bt, Can, Elephant, Eq, Hst, Hu, Mky, Ms, Rb, Rt E, P, WB
50 µg / €425.00
  OriGene Technologies GmbH

3 Item(s)

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