TrkA antibody

Principal name

TrkA antibody

Alternative names for TrkA antibody

NTRK1, TRK, Trk-A, High affinity nerve growth factor receptor, Neurotrophic tyrosine kinase receptor type 1, TRK1-transforming tyrosine kinase protein, p140-TrkA

SwissProt ID

P04629 (Human), P35739 (Rat), Q3UFB7 (Mouse)

Gene ID

4914 (NTRK1), 59109 (Ntrk1), 18211

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Goat, Mouse

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Enzyme Immunoassay (E), Flow Cytometry (F)

Background of TrkA antibody

Trk A (Neurotrophic tyrosine kinase receptor A) is the high affinity catalytic receptor for the neurotrophin, Nerve Growth Factor (NGF). Higher affinity binding of NGFR can achieved by association with higher molecular mass, low-affinity neurotrophin receptors, namely the tropomyosin receptor kinases, TRKA (NTRK1), TRKB (NTRK2), and TRKC (NTRK3). TRKA, TRKB, and TRKC are specific for or 'preferred by' NGF, NTF4(Neurotrophin-4) and BDNF, and NTF3(Neurotrophin-3), respectively. NTF3 also binds to TRKA and TRKB, but with significantly lower affinity. The absence of TrkA(NGFR) expression was associated with a strong increase in the Sp3 repressor short isoform(s) and a lack of the Sp3 activator long isoform. Sp3 is a bifunctional transcription factor that has been reported to stimulate or repress the transcription of numerous genes. Indo et al. (1996) concluded that defects in TRKA cause CIPA (Congenital insensitivity to pain with anhidrosis ) and that the NGF-TRKA system has a crucial role in the development and function of the nociceptive reception as well as establishment of thermoregulation via sweating in humans. These results also implicate genes encoding other TRK and neurotrophin family members as candidates for developmental defect(s) of the nervous system.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TrkA antibody

  Rabbit polyclonal Anti-TrkA (extracellular)  
Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) brain lysates: 1, 2. Anti-TrkA (extracellular) antibody , (1:200). 3, 4. Anti-TrkA (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

TrkA antibody

  Anti-NTRK1 (Phospho-Ser791) Rabbit Polyclonal Antibody  
Predicted band size: 140 kDa . Positive control: Rat and Mouse brain tissue lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1,2: Rat and Mouse brain tissue lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu E
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrkA antibody

  Anti-NTRK1 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human colon and ovarian cancer tissue . Recommended dilution: 1/100-300  The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using NTRK1 antibody at dilution 1/90, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrkA antibody

  Anti-NTRK1 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human colon and lung cancer tissue . Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using NTRK1 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrkA antibody

  Rabbit polyclonal Trk A (Phospho-Tyr791) antibody  
Immunohistochemical analysis of paraffin-embedded human brain tissue, using Trk A (phospho-Tyr791) antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrkA antibody

  Rabbit polyclonal Trk A (Phospho-Tyr701) antibody  
Western blot analysis of extracts from mouse brain cells, using Trk A (Phospho-Tyr701) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrkA antibody

  NTRK1 mouse monoclonal antibody, clone OTI5B6 (formerly 5B6)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-NTRK1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA806413) Mouse IgG1 OTI5B6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

TrkA antibody

Confocal Immunofluorescence analysis of PC-12 cells using TrkA antibody Cat.-No AM06329SU-N (green), showing membrane and cytoplasmic localization. Blue: DRAQ5 fluorescent DNA dye. Mouse IgG1 6B2 Ascites Hu ICC/IF, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

TrkA antibody

Western blot analysis of TrkA expression using Jurkat (Lane 1) and 3T3 (Lane 2) cell lysates. Rabbit Purified Hu, Ms, Rt IP, P, WB
0.1 mg / €370.00
  Acris Antibodies GmbH

TrkA pTyr490 antibody

TrkA Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, IP, P, WB
0.1 mg / €480.00
  Acris Antibodies GmbH

TrkA antibody

Immunohistochemistry (IHC) analyzes of Trk A antibody (Cat.-No.: AP06418PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu ICC/IF, P
0.1 mg / €350.00
  Acris Antibodies GmbH

TrkA antibody

Immunohistochemistry analysis of TrkA Antibody (Cat.-No. AP06589PU-N) in paraffin-embedded Human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

TrkA antibody

AP08798PU-N at 2.5 µg/ml, staining TrkA in Adrenal tissue by Immunohistochemistry (Formalin-Fixed Paraffin-Embedded). Rabbit IgG Aff - Purified Hu, Ms, Rt IP, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

TrkA pSer791 antibody

Figure 1. Immunofluorescence staining of methanol-fixed HeLa cells using TrkA pSer791 Antibody (#AP09480PU, Red). Rabbit Aff - Purified Hu ICC/IF
0.1 ml / €320.00
  Acris Antibodies GmbH

TrkA pSer791 antibody

Figure 1. Immunofluorescence staining of methanol-fixed HeLa cells using TrkA pSer791 Antibody (#AP09480PU, Red). Rabbit Aff - Purified Hu ICC/IF
50 µl / €240.00
  Acris Antibodies GmbH

TrkA antibody

Immunofluorescence staining of methanol-fixed HeLa cells using TrkA Antibody Rabbit Aff - Purified Hu ICC/IF
0.1 ml / €320.00
  Acris Antibodies GmbH

TrkA antibody

Immunofluorescence staining of methanol-fixed HeLa cells using TrkA Antibody Rabbit Aff - Purified Hu ICC/IF
50 µl / €240.00
  Acris Antibodies GmbH

TrkA pTyr791 antibody

Dot blot analysis of anti-Phospho-TrkA-Y791 Pab (Cat.#AP12733PU-N) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. Rabbit Ig Aff - Purified Hu WB

Regular Price: 0.4 ml / €370.00

Special Price: 0.4 ml / €231.00

  Acris Antibodies GmbH

TrkA (Center) antibody

Western blot analysis of anti-TRKA Antibody (Center) Pab in mouse liver tissue lysates (35ug/lane). TRKA(arrow) was detected using the purified polyclonal antibody. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TrkA antibody

Western blot analysis of hTrkA-pY791 (AP18228PU-N) in HepG2 cell line lysates (35ug/lane). TRK (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

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