TRMT12 antibody

Principal name

TRMT12 antibody

Alternative names for TRMT12 antibody

TRM12, TYW2, tRNA wybutosine-synthesizing protein 2 homolog, tRNA-yW-synthesizing protein 2, tRNA methyltransferase 12

SwissProt ID

Q0P466 (Danre), Q4V8B8 (Rat), Q53H54 (Human), Q58D65 (Bovin), Q8BG71 (Mouse)

Gene ID

55039 (TRMT12)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of TRMT12 antibody

TYW2 Antibody: TYW2, also known as TRM12, is an enzyme that participates in the wybutosine-tR (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tR that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW2 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation. TYW2 was found to be amplified in 7 of 8 breast cancers cell lines alyzed, and qPCR alysis of 30 breast tumors showed overexpression of TYW2 mR of over 2-fold in 26, suggesting that TYW2 may play a role in breast cancer.

11 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TRMT12 (N-term) antibody

Western blot analysis of TYW2 in K562 cell lysate with TYW2 antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TRMT12 control peptide

TRMT12
50 µg / €160.00
  Acris Antibodies GmbH

TRMT12 antibody

Western Blot analysis of TRMT12 expression in transfected 293T cell line (H00055039-T01) by TRMT12 MaxPab polyclonal antibody.

Lane 1: TRMT12 transfected lysate(49.28 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

TRMT12 antibody

TRMT12 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

TRMT12 antibody

TRMT12 Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

TRMT12 antibody

Immunohistochemistry-Paraffin: TRMT12 Antibody [NBP1-83633] - Immunohistochemical staining of human colon shows moderate nuclear positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TRMT12 (full length, N-term HIS tag)

TRMT12 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

TRMT12

TRMT12 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

TRMT12

TRMT12 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

TRMT12 293T Cell Transient Overexpression Lysate(Denatured)

TRMT12 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

TRMT12 overexpression lysate

TRMT12 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

11 Item(s)

per page
  • LinkedIn