Tropomyosin-1 (TPM1) antibody

Principal name

Tropomyosin-1 (TPM1) antibody

Alternative names for Tropomyosin-1 (TPM1) antibody

Tropomyosin alpha-1 chain, Alpha-tropomyosin, TMSA, C15orf13

SwissProt ID

P04268 (Chick), P09493 (Human), P42639 (Pig), P58771 (Mouse), P58772 (Rabit), Q5KR49 (Bovin)

Gene ID

7168 (TPM1), 396366, 22003 (Tpm1)

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Chk (Chicken), Rb (Rabbit), Bov (Bovine), Por (Porcine), Eq (Equine), GP (Guinea Pig), Sh (Sheep)

Available hosts

Rabbit, Mouse, Sheep

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Enzyme Immunoassay (E)

Background of Tropomyosin-1 (TPM1) antibody

TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction.This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.

General readings

Lin,J.C. (2005) Mol. Cell. Biol. 25 (22), 10111-10121

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Tropomyosin-1 (TPM1) antibody

  Anti-TPM1 Rabbit Polyclonal Antibody  
Predicted band size: 33 kDa . Positive control: Mouse heart and muscle tissue lysate. Recommended dilution: 1/500-2000. (Gel: 12%SDS-PAGE Lane1: Mouse heart tissue lysate Lane2: Mouse muscle tissue lysate Lysates: 50 ug per lane Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) antibody

  Anti-TPM1 Rabbit Polyclonal Antibody  
Predicted band size: 33 kDa . Positive control: Mouse heart tissue lysate. Recommended dilution: 1/1000-5000. (Gel: 12%SDS-PAGE Lysate: 50 ug per lane Primary antibody: 1/1000 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) antibody

  TPM1 Rabbit Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using TPM1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €335.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) antibody

  Rabbit Polyclonal Anti-TPM1 Antibody  
WB Suggested Anti-TPM1 Antibody Titration: 1.25 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Sh, Ze P, WB
0.1 mg / €360.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) antibody

  Rabbit Polyclonal Anti-TPM1 Antibody  
WB Suggested Anti-TPM1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human brain Rabbit IgG Purified Hu, Ms, Rt WB
50 µg / €360.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) (36/39kDa) antibody

Tropomyosin-1 (TPM1) Mouse IgG1 TM-33 Purified Chk, Hu, Ms, Rt WB
0.1 mg / €390.00
  OriGene Technologies GmbH

Tropomyosin-1 (TPM1) (36Da) antibody

Tropomyosin-1 (TPM1) Mouse IgG2a TM-36 Purified Chk, Hu, Ms, Rt C, ICC/IF, WB
0.1 mg / €390.00
  OriGene Technologies GmbH

Tropomyosin-1 (TPM1) (Sarcomeric) antibody

Tropomyosin-1 (TPM1) Mouse IgG1 ST-39 Purified Chk, Hu, Rb, Rt C, ICC/IF, IP, P, WB
0.1 mg / €390.00
  OriGene Technologies GmbH

Tropomyosin-1 (TPM1) (92-283) antibody

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu, Ms P, WB
50 µl / €380.00
  OriGene Technologies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Tropomyosin-1 (TPM1) (transcript variant 5)

  Recombinant protein of human tropomyosin 1 (alpha) (TPM1), transcript variant 5  
Tropomyosin-1 (TPM1) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) (transcript variant 1)

  Purified recombinant protein of Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 1  
Tropomyosin-1 (TPM1) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €438.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) (transcript variant 7)

  Purified recombinant protein of Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 7  
Tropomyosin-1 (TPM1) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €438.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) (transcript variant 3)

  Purified recombinant protein of Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 3  
Tropomyosin-1 (TPM1) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €438.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) (transcript variant 4)

  Purified recombinant protein of Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 4  
Tropomyosin-1 (TPM1) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) (transcript variant 2)

  Purified recombinant protein of Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 2  
Tropomyosin-1 (TPM1) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) (transcript variant 5)

  Recombinant protein of human tropomyosin 1 (alpha) (TPM1), transcript variant 5  
Tropomyosin-1 (TPM1) Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €399.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) (1-284, His-tag)

Recombinant human TPM1, 1-284aa, His-tagged Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €750.00
  OriGene Technologies GmbH

Tropomyosin-1 (TPM1) (1-284, His-tag)

Recombinant human TPM1, 1-284aa, His-tagged Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  OriGene Technologies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TPM1 (mGFP-tagged)-Human tropomyosin 1 (alpha) (TPM1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, TPM1 (mGFP-tagged)-Human tropomyosin 1 (alpha) (TPM1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €989.00
  OriGene Technologies, Inc.

Lenti ORF particles, TPM1 (mGFP-tagged)-Human tropomyosin 1 (alpha) (TPM1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, TPM1 (mGFP-tagged)-Human tropomyosin 1 (alpha) (TPM1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €989.00
  OriGene Technologies, Inc.

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