Tropomyosin-1 (TPM1) antibody

Principal name

Tropomyosin-1 (TPM1) antibody

Alternative names for Tropomyosin-1 (TPM1) antibody

Tropomyosin alpha-1 chain, Alpha-tropomyosin, TMSA, C15orf13

SwissProt ID

P04268 (Chick), P09493 (Human), P42639 (Pig), P58771 (Mouse), P58772 (Rabit), Q5KR49 (Bovin)

Gene ID

7168 (TPM1), 396366, 22003 (Tpm1)

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Chk (Chicken), Rb (Rabbit), Bov (Bovine), Por (Porcine), Eq (Equine), GP (Guinea Pig), Sh (Sheep)

Available hosts

Rabbit, Mouse, Sheep

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Enzyme Immunoassay (E)

Background of Tropomyosin-1 (TPM1) antibody

TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction.This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.

General readings

Lin,J.C. (2005) Mol. Cell. Biol. 25 (22), 10111-10121

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Tropomyosin-1 (TPM1) antibody

  Anti-TPM1 Rabbit Polyclonal Antibody  
Predicted band size: 33 kDa . Positive control: Mouse heart and muscle tissue lysate. Recommended dilution: 1/500-2000. (Gel: 12%SDS-PAGE Lane1: Mouse heart tissue lysate Lane2: Mouse muscle tissue lysate Lysates: 50 ug per lane Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) antibody

  Anti-TPM1 Rabbit Polyclonal Antibody  
Predicted band size: 33 kDa . Positive control: Mouse heart tissue lysate. Recommended dilution: 1/1000-5000. (Gel: 12%SDS-PAGE Lysate: 50 ug per lane Primary antibody: 1/1000 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) antibody

  TPM1 Rabbit Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using TPM1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) antibody

  Rabbit Polyclonal Anti-TPM1 Antibody  
WB Suggested Anti-TPM1 Antibody Titration: 1.25 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Sh, Ze P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) antibody

  Rabbit Polyclonal Anti-TPM1 Antibody  
WB Suggested Anti-TPM1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human brain Rabbit IgG Purified Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) antibody

  Sheep polyclonal anti-Human Skeletal Muscle Tropomyosin antibody  
Tropomyosin-1 (TPM1) Sheep IgG Purified Hu, Ms, Rt WB
100 µl / €325.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) antibody

  Sheep polyclonal anti-Skeletal Muscle alpha-Tropomyosin antibody  
Tropomyosin-1 (TPM1) Sheep IgG Purified Hu, Ms, Rb, Rt WB
100 µl / €325.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) (36/39kDa) antibody

Tropomyosin-1 (TPM1) Mouse IgG1 TM-33 Purified Chk, Hu, Ms, Rt WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Tropomyosin-1 (TPM1) (36Da) antibody

Tropomyosin-1 (TPM1) Mouse IgG2a TM-36 Purified Chk, Hu, Ms, Rt C, ICC/IF, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Tropomyosin-1 (TPM1) (Sarcomeric) antibody

Tropomyosin-1 (TPM1) Mouse IgG1 ST-39 Purified Chk, Hu, Rb, Rt C, ICC/IF, IP, P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Tropomyosin-1 (TPM1) (92-283) antibody

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Bov, Hu, Ms, Por, Rb, Rt P, WB
50 µl / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

TPM1 - human gene knockout kit via CRISPR

TPM1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

TPM1 - human gene knockout kit via CRISPR

TPM1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

TPM1 - human gene knockout kit via CRISPR

TPM1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

TPM1 - human gene knockout kit via CRISPR

TPM1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Tropomyosin-1 (TPM1) (transcript variant 5)

  Recombinant protein of human tropomyosin 1 (alpha) (TPM1), transcript variant 5  
Tropomyosin-1 (TPM1) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) (transcript variant 1)

  Purified recombinant protein of Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 1  
Tropomyosin-1 (TPM1) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) (transcript variant 7)

  Purified recombinant protein of Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 7  
Tropomyosin-1 (TPM1) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) (transcript variant 3)

  Purified recombinant protein of Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 3  
Tropomyosin-1 (TPM1) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Tropomyosin-1 (TPM1) (transcript variant 4)

  Purified recombinant protein of Homo sapiens tropomyosin 1 (alpha) (TPM1), transcript variant 4  
Tropomyosin-1 (TPM1) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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