Tropomyosin-1 (TPM1) antibody
Principal name
Tropomyosin-1 (TPM1) antibody
Alternative names for Tropomyosin-1 (TPM1) antibody
Tropomyosin alpha-1 chain, Alpha-tropomyosin, TMSA, C15orf13
SwissProt ID
P04268 (Chick), P09493 (Human), P42639 (Pig), P58771 (Mouse), P58772 (Rabit), Q5KR49 (Bovin)
Ncbi ID
9606, NP_000357, NP_990732, NP_000357.3, NP_001018005, NP_001018020, NP_001018004, NP_001018006, NP_001018007, NM_024427, NM_001164248, NM_001164251, NM_001164254, NM_001164249, NM_001164255, NM_001164250, NM_001018008, NM_001018005, NM_001018004, NM_001018006, NM_001018007
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Enzyme Immunoassay (E)
Background of Tropomyosin-1 (TPM1) antibody
TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction.This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.
General readings
Lin,J.C. (2005) Mol. Cell. Biol. 25 (22), 10111-10121









Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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TA346033 | Tropomyosin-1 (TPM1) antibody |
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Rabbit Polyclonal Anti-TPM1 Antibody | |||||||
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Rabbit | IgG | Purified | Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Sh, Ze | P, WB |
0.1 ml /
€300.00
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OriGene Technologies, Inc. | |||||||
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AP23588PU-N | Tropomyosin-1 (TPM1) (92-283) antibody |
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Rabbit | Aff - Purified | Hu, Ms | P, WB |
50 µl /
€425.00
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OriGene Technologies GmbH | |||||||
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