Tropomyosin-3 (TPM3) antibody

Principal name

Tropomyosin-3 (TPM3) antibody

Alternative names for Tropomyosin-3 (TPM3) antibody

Tropomyosin alpha-3 chain, Gamma-tropomyosin, Tropomyosin-5, TPM5

SwissProt ID

A1XQV4 (Pig), P06753 (Human), P21107 (Mouse), Q5KR47 (Bovin), Q63610 (Rat)

Gene ID

7170 (TPM3), 117557 (Tpm3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Ze (Zebrafish), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Tropomyosin-3 (TPM3) antibody

TPM3 is a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer.This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

General readings

Ohtsuki I., et al. (2002) J Biochem. 131:739-743.Tiso N., et al. (1997) Biochem Biophys Res Commun. 230:347-350.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Tropomyosin-3 (TPM3) antibody

  TPM3 Rabbit Polyclonal Antibody  
Western blot analysis of 293T cell and A431 cell lysate using TPM3 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Tropomyosin-3 (TPM3) antibody

  Rabbit Polyclonal Anti-TPM3 Antibody  
WB Suggested Anti-TPM3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Tropomyosin-3 (TPM3) (1-249) antibody

Formalin-Fixed, Paraffin-Embedded Human Heart stained with  TPM3 Antibody Cat.-No AM32450PU-N Mouse IgG2a 2E4 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

TPM3 - human gene knockout kit via CRISPR

TPM3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

TPM3 - human gene knockout kit via CRISPR

TPM3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

TPM3 - human gene knockout kit via CRISPR

TPM3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

TPM3 - human gene knockout kit via CRISPR

TPM3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Tropomyosin-3 (TPM3) (transcript variant 1)

  Recombinant protein of human tropomyosin 3 (TPM3), transcript variant 1  
Tropomyosin-3 (TPM3) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Tropomyosin-3 (TPM3) (transcript variant 2)

  Recombinant protein of human tropomyosin 3 (TPM3), transcript variant 2  
Tropomyosin-3 (TPM3) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Tropomyosin-3 (TPM3) (transcript variant 4)

  Recombinant protein of human tropomyosin 3 (TPM3), transcript variant 4  
Tropomyosin-3 (TPM3) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Tropomyosin-3 (TPM3) (transcript variant 5)

  Purified recombinant protein of Homo sapiens tropomyosin 3 (TPM3), transcript variant 5  
Tropomyosin-3 (TPM3) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Tropomyosin-3 (TPM3) (1-248, His-tag)

Tropomyosin-3 (TPM3) Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €730.00
  Acris Antibodies GmbH

Tropomyosin-3 (TPM3) (1-248, His-tag)

Tropomyosin-3 (TPM3) Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

TPM3 overexpression lysate

TPM3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

TPM3 overexpression lysate

TPM3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

TPM3 overexpression lysate

TPM3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

TPM3 overexpression lysate

TPM3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

TPM3 overexpression lysate

TPM3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TPM3 (mGFP-tagged) - Human tropomyosin 3 (TPM3), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, TPM3 (mGFP-tagged) - Human tropomyosin 3 (TPM3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, TPM3 (mGFP-tagged) - Human tropomyosin 3 (TPM3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, TPM3 (mGFP-tagged) - Human tropomyosin 3 (TPM3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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