TRPC1 / TRP1 antibody

Principal name

TRPC1 / TRP1 antibody

Alternative names for TRPC1 / TRP1 antibody

Transient receptor protein 1, TRP-1, Short transient receptor potential channel 1

SwissProt ID

O18784 (Bovin), P48995 (Human), Q61056 (Mouse), Q9QX01 (Rat), Q9TUN9 (Rabit)

Gene ID

7220 (TRPC1), 89821 (Trpc1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine)

Available hosts

Mouse, Sheep, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of TRPC1 / TRP1 antibody

The Transient Receptor Potential (TRP) superfamily is one of the largest ion channel families and consists of diverse groups of proteins. In mammals about 28 genes encode the TRP ion channel subunits. The mammalian TRP superfamily comprises six subfamilies known as the TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPML (mucolipins), TRPP (polycystin) and the TRPA (ANKTM1) ion channels. The TRPC subfamily consists of seven proteins med TRPC1 to 7, which can be further divided into four subgroups based on their sequence homology and functiol similarities: 1.) TRPC1 2.) TRPC4 and TRPC5 3.) TRPC3, TRPC6, TRPC7 4.) TRPC2. They are highly expressed in the central nervous system and to a lesser extent in peripheral tissues. TRPC1 was the first mammalian TRP protein that was reported to form an ion channel. It can co-assemble with other TRPC subunits (TRPC3, TRPC4, TRPC5) to form heterotetramers whose properties are distinct from that of their homomeric form. The existence of the TRPC1 homomers has not been established as yet. The TRPC1, TRPC4 and TRPC5 can be activated either by Ca2+, store depletion or by GPCR stimulation pathways, while TRPC3, TRPC6 and TRPC7 form non-selective cationic channels that are activated by the stimulation of GPCRs. TRPC1, 4 and TRPC5 are assumed to form components of store operated channels in some cell types such as salivary gland cells, endothelial cells and vascular smooth muscle cells.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TRPC1 / TRP1 antibody

Immunohistochemistry: TRP-1 Antibody [NB100-98844] - IF (confocal) on rat trigeminal at 1 : 500 dilution using Rabbit antibody to 2d extracellular loop of TRPC1: whole serum, DAPI counterstained appearing in blue. Rabbit Serum Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

TRPC1 / TRP1 antibody

Western blot analysis of rat brain membranes: 1. Anti-TRPC1 antibody, (1:200). 2. Anti-TRPC1 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

TRPC1 / TRP1 antibody

Western blot analysis of rat brain lysate: 1. Anti-TRPC1 (extracellular) antibody, (1:200). 2. Anti-TRPC1 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

TRPC1 / TRP1 (722-733) antibody

Prostate, fibromuscular stroma, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bear, Bov, Bt, Can, Chk, Elephant, Eq, Fi, Hu, L, Mky, Ms, Op, Platypus, Por, Prim, Rb, Rt, Tr, Xen P
50 µg / €470.00
  Acris Antibodies GmbH

TRPC1 / TRP1 (C-term) antibody

TRPC1 Antibody (C-term) (AP54359PU-N) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the TRPC1 antibody detected the TRPC1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TRPC1 / TRP1 antibody

TRPC1 / TRP1 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

TRPC1 / TRP1 antibody

TRPC1 / TRP1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

TRPC1 / TRP1 antibody

TRPC1 / TRP1 Mouse IgG2b 1E4 Hu E
50 µg / €370.00
  Abnova Taiwan Corp.

TRPC1 / TRP1 antibody

TRPC1 / TRP1 Mouse IgG2b 1E4 Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

TRPC1 / TRP1 antibody

TRPC1 / TRP1 Sheep Serum Hu, Ms, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

TRPC1 / TRP1 antibody

TRPC1 / TRP1 Goat Aff - Purified Can, Hu, Ms, Rt P
50 µg / €480.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TRPC1 / TRP1

TRPC1 / TRP1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TRPC1 / TRP1

TRPC1 / TRP1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

TRPC1 overexpression lysate

TRPC1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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