TRPC1 / TRP1 antibody

Principal name

TRPC1 / TRP1 antibody

Alternative names for TRPC1 / TRP1 antibody

Transient receptor protein 1, TRP-1, Short transient receptor potential channel 1

SwissProt ID

O18784 (Bovin), P48995 (Human), Q61056 (Mouse), Q9QX01 (Rat), Q9TUN9 (Rabit)

Gene ID

7220 (TRPC1), 89821 (Trpc1), 22063

Available reactivities

Hu (Human), Bt (Bat), Bov (Bovine), Can (Canine), Chk (Chicken), Eq (Equine), Fi (Fish), Mky (Monkey), Ms (Mouse), Op (Opossum), Por (Porcine), Prim (Primate), Rb (Rabbit), Rt (Rat), Xen (Xenopus), Tr (Turkey), L (Lizard), Bear

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C)

Background of TRPC1 / TRP1 antibody

The Transient Receptor Potential (TRP) superfamily is one of the largest ion channel families and consists of diverse groups of proteins. In mammals about 28 genes encode the TRP ion channel subunits. The mammalian TRP superfamily comprises six subfamilies known as the TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPML (mucolipins), TRPP (polycystin) and the TRPA (ANKTM1) ion channels. The TRPC subfamily consists of seven proteins med TRPC1 to 7, which can be further divided into four subgroups based on their sequence homology and functiol similarities: 1.) TRPC1 2.) TRPC4 and TRPC5 3.) TRPC3, TRPC6, TRPC7 4.) TRPC2. They are highly expressed in the central nervous system and to a lesser extent in peripheral tissues. TRPC1 was the first mammalian TRP protein that was reported to form an ion channel. It can co-assemble with other TRPC subunits (TRPC3, TRPC4, TRPC5) to form heterotetramers whose properties are distinct from that of their homomeric form. The existence of the TRPC1 homomers has not been established as yet. The TRPC1, TRPC4 and TRPC5 can be activated either by Ca2+, store depletion or by GPCR stimulation pathways, while TRPC3, TRPC6 and TRPC7 form non-selective cationic channels that are activated by the stimulation of GPCRs. TRPC1, 4 and TRPC5 are assumed to form components of store operated channels in some cell types such as salivary gland cells, endothelial cells and vascular smooth muscle cells.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TRPC1 / TRP1 antibody

  Rabbit Polyclonal Anti-TRPC1  
Western blot analysis of rat brain membranes: 1. Anti-TRPC1 antibody, (1:200). 2. Anti-TRPC1 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

TRPC1 / TRP1 antibody

  Rabbit Polyclonal Anti-TRPC1 (extracellular)  
Western blot analysis of rat brain lysate: 1. Anti-TRPC1 (extracellular) antibody, (1:200). 2. Anti-TRPC1 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

TRPC1 / TRP1 (722-733) antibody

Prostate, fibromuscular stroma, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bear, Bov, Bt, Can, Chk, Elephant, Eq, Fi, Hu, L, Mky, Ms, Op, Platypus, Por, Prim, Rb, Rt, Tr, Xen P
50 µg / €470.00
  Acris Antibodies GmbH

TRPC1 / TRP1 (C-term) antibody

TRPC1 Antibody (C-term) (AP54359PU-N) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the TRPC1 antibody detected the TRPC1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TRPC1 / TRP1 antibody

TRPC1 / TRP1 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

TRPC1 / TRP1 antibody

TRPC1 / TRP1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

TRPC1 / TRP1 antibody

TRPC1 / TRP1 Mouse IgG2b 1E4 Hu E
50 µg / €370.00
  Abnova Taiwan Corp.

TRPC1 / TRP1 antibody

TRPC1 / TRP1 Mouse IgG2b 1E4 Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

CRISPR

Catalog No. Species Donor Vector  

TRPC1 - human gene knockout kit via CRISPR

TRPC1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

TRPC1 - human gene knockout kit via CRISPR

TRPC1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

TRPC1 - human gene knockout kit via CRISPR

TRPC1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

TRPC1 - human gene knockout kit via CRISPR

TRPC1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Trpc1 - mouse gene knockout kit via CRISPR

Trpc1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Trpc1 - mouse gene knockout kit via CRISPR

Trpc1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Trpc1 - mouse gene knockout kit via CRISPR

Trpc1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Trpc1 - mouse gene knockout kit via CRISPR

Trpc1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TRPC1 / TRP1

TRPC1 / TRP1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TRPC1 / TRP1

TRPC1 / TRP1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

TRPC1 overexpression lysate

TRPC1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TRPC1 (mGFP-tagged) - Human transient receptor potential cation channel, subfamily C, member 1 (TRPC1), 200 uL, >10^7 TU/mL

Lenti ORF particles, TRPC1 (mGFP-tagged) - Human transient receptor potential cation channel, subfamily C, member 1 (TRPC1), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

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