TRPC6 / TRP6A antibody

Principal name

TRPC6 / TRP6A antibody

Alternative names for TRPC6 / TRP6A antibody

Transient receptor potential Ca2+ channel 6A

SwissProt ID

Q99N78 (Rat)

Gene ID


Ncbi ID


Available reactivities

Rt (Rat)

Available hosts


Available applications

Frozen Sections (C), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of TRPC6 / TRP6A antibody

The TRP isoforms can be divided into three subfamilies based on characteristic sequence domains. The long TRP channels (LTRPCs) have four related sequences with open reading frames (ORFs) coding for approximately 1600 amino acids. The other two subfamilies are characterized by shorter ORFs, coding for about 900 amino acids. These are called the short TRP (STRP) and osm-9-like (OTRP) channel families. Human TRPC6 is a 931 amino acid protein. TRPC6 has been identified in placenta, lung, spleen, ovary and small intestine by Northern analysis. Human TRPC6 is a non-selective cation channel that is activated by diacylglycerol in a membrane-delimited fashion. Additionally, human TRPC6, and its close structural relative TRPC3, are the only two molecularly defined channels that are directly activated by diacylglycerols independently of protein kinase C.

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