TRPM1 / LTRPC1 antibody

Principal name

TRPM1 / LTRPC1 antibody

Alternative names for TRPM1 / LTRPC1 antibody

Melastatin-1, MLSN, MLSN1, Transient receptor potential cation channel subfamily M member 1, Long transient receptor potential channel 1

SwissProt ID

Q2TV84 (Mouse), Q2WEA5 (Rat), Q7Z4N2 (Human)

Gene ID

4308 (TRPM1), 17364 (Trpm1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Sheep

Available applications

Frozen Sections (C), Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of TRPM1 / LTRPC1 antibody

The mammalian melastatin-related transient receptor potential (TRPM) is a subfamily of the TRP family. The family was med after the first discovered member melastatin (TRPM1) whose gene was identified in metastatic and benign melanomas. The TRPM family consist of eight members desigted as TRPM1-8 that can be further divided into four pairs: TRPM1 and TRPM3; TRPM2 and TRPM8; TRPM4 and TRPM5; and TRPM6 and TRPM7. The TRPM proteins share structural homology with other members of the TRP superfamily channels; six putative transmembrane domains, and cytoplasmic N-terminus and C-terminus. However, due to their long N-terminus and C-terminus they were also med the long TRP channel family. TRPM channels were suggested to play a role in tumourigenesis, proliferation and differentiation. Recently, TRPM1 was found to be down-regulated in a highly metastatic line. The loss of TRPM1 expression has been reported to be correlated to melanoma aggressiveness. Two altertive splice variants of TRPM1 were reported; short (TRPM1-S) and long (TRPM1-L). The TRPM1-S was described to be expressed at human melanocyte and mainly in metastasic melanoma cell lines. While TRPM1-L is expressed at murine CNS.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TRPM1 / LTRPC1 antibody

Predicted cell location: Cytoplasm. Positive control: Human liver and lung cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using TRPM1 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TRPM1 / LTRPC1 antibody

Western blot analysis of A875 (human melanoma cell line) lysate: 1. Anti-Human TRPM1 antibody, (1:200). 2. Anti-Human TRPM1 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

TRPM1 / LTRPC1 (middle region) antibody

TRPM1 / LTRPC1 Rabbit Aff - Purified Ms ELISA, WB
25 µg / €630.00
  Funakoshi Co., Ltd.

TRPM1 / LTRPC1 antibody

TRPM1 / LTRPC1 Rabbit Serum Hu C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

TRPM1 / LTRPC1 antibody

TRPM1 / LTRPC1 Sheep Serum Ms C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

TRPM1 / LTRPC1 antibody

Immunohistochemistry-Paraffin: TRPM1 Antibody [NBP1-81284] Immunohistochemical staining of human colon shows strong cytoplasmic and membranous positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates (Overexpressed)

Catalog No.    

TRPM1 overexpression lysate

TRPM1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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