TRPM2 / TRPC7 antibody

Principal name

TRPM2 / TRPC7 antibody

Alternative names for TRPM2 / TRPC7 antibody

EREG1, KNP3, LTRPC2, LTrpC-2, LTrpC2, Transient receptor potential cation channel subfamily M member 2, Estrogen-responsive element-associated gene 1 protein, Long transient receptor potential channel 2, Transient receptor potential channel 7

SwissProt ID

O94759 (Human), Q5G856 (Rat), Q91YD4 (Mouse)

Gene ID

7226 (TRPM2), 294329, 28240 (Trpm2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Goat

Available applications

Paraffin Sections (P), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Immunohistochemistry (IHC)

Background of TRPM2 / TRPC7 antibody

The mammalian melastatin-related transient receptor potential (TRPM) is a subfamily of the TRP family. The family was med after the first discovered member, melastatin (TRPM1) whose gene was identified in metastatic and benign melanomas. The TRPM family consists of eight members desigted as TRPM1-8 that can be further divided into four pairs: TRPM1 and TRPM3; TRPM2 and TRPM8; TRPM4 and TRPM5; and TRPM6 and TRPM7. The TRPM proteins share structural homology with other members of the TRP superfamily channels; six putative transmembrane domains, and cytoplasmic N- and C-termini. However, due to their long N- and C-termini they are also med the long TRP channel family. The C-termil regions of three TRPM members (TRPM2, TRPM 6 and TRPM 7) are occupied by enzymatic domains. Almost all the C-termil region of TRPM2 has an enzymatic domain with sequence similarities to Nudix hydrolases (cleave mononucleotide and dinucleotide polyphosphates. TRPM2 is a Ca2+-permeable, nonselective cation channel that is predomintly expressed in various regions of the brain, where it is preferentially localized in microglial cells, the host macrophages of the central nervous system and is also expressed in other tissues, including spleen, heart, liver, lung, and bone marrow. Several splice variants of TRPM2 have been identified.

General readings

Hecquet,C.M., (2008) Circ. Res. 102 (3), 347-355

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TRPM2 / TRPC7 antibody

Anti-TRPM2 antibody, PA2231, IHC(P).IHC(P): Human Tonsil Tissue. Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

TRPM2 / TRPC7 antibody

Sample (30 ug of whole cell lysate). A: Hep G2 . 7.5% SDS PAGE. TA308572 diluted at 1:500. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TRPM2 / TRPC7 antibody

Western blot analysis of rat lung membrane (lanes 1 and 4), rat brain membrane (lanes 2 and 5) and human K562 cells (lanes 3 and 6) lysates: 1-3. Anti-TRPM2 antibody, (1:200). 4-6. Anti-TRPM2 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

TRPM2 / TRPC7 antibody

TRPM2 antibody - N-terminal region validated by WB using Fetal Brain Lysate at 1 ug/ml. Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

TRPM2 / TRPC7 antibody

Western Blot: TRPM2 Antibody [TA336551] - Lane 1: CHO cells untransfected. Lane 2: CHO cell transfected with rat TRPM2 Lane 3: Mouse cortical neurons (cultured) Photo courtesy of Dr. Paco Herson, Oregon Health & Science University. Rabbit Purified Ms, Rt C, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TRPM2 / TRPC7 antibody

Western Blot: TRPM2 Antibody [TA336554] - Detection of TRPM2 in mouse brain membrane lysates using TA336554. Rabbit Purified Ms, Rt ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TRPM2 / TRPC7 (1139-1150) antibody

Pancreas, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bov, Bt, Hu, Mky, Ms, Prim, Rt P
50 µg / €470.00
  Acris Antibodies GmbH

TRPM2 / TRPC7 (long isoform) antibody

Immunohistochemical staining of Trpm2 on rat hippocampus with Trpm2 polyclonal antibody ( Cat # PAB11990 ). TRPM2 is stained red, GFAP is stained green and nuclei staining is blue. Photo courtesy of Dr. Ji-Zhong Bai, The University of Auckland, New Zealand. Rabbit Ms, Rt C, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

TRPM2 / TRPC7 antibody

Western blot analysis of Trpm2 in mouse brain membrane lysates with Trpm2 polyclonal antibody ( Cat # PAB11991 ). Rabbit Ms, Rt WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

TRPM2 / TRPC7 antibody

Human, Mouse; Immunohistochemistry with human LCL and mouse brains incubated for 5 minutes in CDP-Star for 5 minutes tissue; TRPM2 antibody - N-terminal region (ARP44380_P050) in Human, Mouse cells using Immunohistochemistry Rabbit Aff - Purified Bov, Hu, Ms, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

TRPM2 / TRPC7 (middle region) antibody

TRPM2 / TRPC7 Rabbit Aff - Purified Ms ELISA, ICC/IF
25 µg / €630.00
  Funakoshi Co., Ltd.

TRPM2 / TRPC7 (C-term) antibody

TRPM2 / TRPC7 Rabbit Aff - Purified Hu, Ms, Rt ELISA, ICC/IF, IHC, WB
25 µg / €630.00
  Funakoshi Co., Ltd.

TRPM2 / TRPC7 (long isoform) antibody

TRPM2 / TRPC7 Rabbit Biotin Ms, Rt P, WB
0.1 ml / €360.00
  Novus Biologicals Inc.

TRPM2 / TRPC7 (long isoform) antibody

TRPM2 / TRPC7 Rabbit DyLight488 Ms, Rt P, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

TRPM2 / TRPC7 (long isoform) antibody

TRPM2 / TRPC7 Rabbit HRP Ms, Rt P, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

TRPM2 / TRPC7 Control Peptide

TRPM2 / TRPC7
50 µl / €140.00
  Novus Biologicals Inc.

TRPM2 / TRPC7 (long isoform) antibody

TRPM2 / TRPC7 Rabbit Aff - Purified Ms, Rt ICC/IF, P, WB
25 µl / €200.00
  Novus Biologicals Inc.

TRPM2 / TRPC7 antibody

TRPM2 / TRPC7 Rabbit Biotin Ms, Rt WB
0.1 ml / €360.00
  Novus Biologicals Inc.

TRPM2 / TRPC7 antibody

TRPM2 / TRPC7 Rabbit DyLight488 Ms, Rt WB
0.1 ml / €390.00
  Novus Biologicals Inc.

TRPM2 / TRPC7 antibody

TRPM2 / TRPC7 Rabbit HRP Ms, Rt WB
0.1 ml / €390.00
  Novus Biologicals Inc.

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