TRPV1 / Vanilloid receptor 1 antibody

Principal name

TRPV1 / Vanilloid receptor 1 antibody

Alternative names for TRPV1 / Vanilloid receptor 1 antibody

VR1, Capsaicin receptor, OTRPC1, Transient receptor potential cation channel subfamily V member 1, Osm-9-like TRP channel 1

SwissProt ID

O35433 (Rat), Q697L1 (Canfa), Q6R5A3 (Cavpo), Q6RX08 (Rabit), Q704Y3 (Mouse), Q8NER1 (Human)

Gene ID

83810 (Trpv1), 193034, 7442 (TRPV1)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Prim (Primate), Rb (Rabbit), GP (Guinea Pig), Mky (Monkey)

Available hosts

Guinea Pig, Rabbit, Goat, Mouse, Sheep

Available applications

Frozen Sections (C), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Background of TRPV1 / Vanilloid receptor 1 antibody

TRPV1 (also med VR1, capsaicin receptor and vanilloid receptor) is a member of the transient receptor potential (TRP) channel family, which includes TRPC, TRPM, TRPA, TRPP, TRPML and the TRPV subfamilies. The TRPV subfamily consists of six members med, TRPV1-6. The TRPV1 channel is a vanilloid gated, nonselective cation channel. The channel has sequence homology to the TRP family, and shares a similar predicted structure of six transmembrane domain (TM) with a pore loop between TM5 and TM6. TRPV1 is expressed predomintly in nociceptors and in sensory neurons. TRPV1 has many activators among them heat, protons, vanilloids like capsaicin, resiniferatoxin (RTX), and lipids. This channel is associated with tissue injury and inflammation. Other members of this family, TRPV2, TRPV3 and TRPV4 also show thermal sensitivity. Conformatiol changes in the C-terminus are responsible for many functions such as permeation and gating. There is also evidence that deletion of the C-terminus causes a loss of sensitivity to any stimuli. Recent studies demonstrated involvement of TRPV1 in apoptosis where inhibition of the receptor prevented apoptosis.

General readings

Guo A et al. Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites. Eur J Neurosci 11:946-58 (1999). PubMed PMID: 10103088
Caterina MJ et al. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389:816-24 (1997). PubMed PMID: 9349813

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TRPV1 / Vanilloid receptor 1 antibody

Western blot analysis of TRPV1 transfected HEK-293 cells: 1. Anti-TRPV1 antibody, (1:200). 2. Anti-TRPV1 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

TRPV1 / Vanilloid receptor 1 antibody

Immunohistochemistry: TRPV1 Antibody - IHC analysis of TRPV1 in mouse dorsal root ganglion using DAB with hematoxylin counterstain. Rabbit Purified Hu, Ms C, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

TRPV1 / Vanilloid receptor 1 antibody

Western blot analysis of TRPV1 in K562 cell lysate with TRPV1 antibody at 1 ug/mL. Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TRPV1 / Vanilloid receptor 1 antibody

Western blot analysis of TRPV1 in rat DRG: 1. Anti-Rat TRPV1 (extracellular) antibody, (1:200). 2. Anti-Rat TRPV1 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

TRPV1 / Vanilloid receptor 1 antibody

Western Blot: TRPV1 Antibody [TA336871] - WB analysis of TRPV1 in 1. Ntera2 cell lysate, 2. HepG2 cell lysate, 3. MCF7 cell lysate and 4. Cos7 cell lysate. Rabbit Purified Hu, Ms, Prim, Rt ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TRPV1 / Vanilloid receptor 1 antibody

Anti-TRPV1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu, Mky
50 µg / €379.00
  OriGene Technologies, Inc.

TRPV1 / Vanilloid receptor 1 antibody

Immunofluorescence staining of adult dorsal root ganglion sections from TrpV1 WT and KO -/- mice with N221/17 TC supe (red), Kv1.2 rabbit polyclonal (green) and Hoechst nuclear stain (blue). Images courtesy of Matt Rasband (Baylor College of Medicine). Mouse IgG1 N221/17 Supernatant Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

TRPV1 / Vanilloid receptor 1 antibody

Transfected cell immunoblot: extracts of COS-1 cells transiently transfected with HA-tagged TrpV1 or untagged Kv2.1 plasmids and probed with N221/12 (left panel) or N52A/42 (right panel) TC supe. Mouse IgG1 N221/12 Supernatant Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

TRPV1 / Vanilloid receptor 1 antibody

Immunofluorescence staining of adult dorsal root ganglion sections from TrpV1 WT and KO -/- mice with N221/17 TC supe (red), Kv1.2 rabbit polyclonal (green) and Hoechst nuclear stain (blue). Images courtesy of Matt Rasband (Baylor College of Medicine). Mouse IgG1 N221/17 Purified Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

TRPV1 / Vanilloid receptor 1 (N-term) antibody

Immunohistochemistry with TRPV1 polyclonal antibody Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

TRPV1 / Vanilloid receptor 1 (105-115) antibody

Western blot analysis of extracts from mouse brain using anti-TRPV1 rabbit whole antiserum. Rabbit Azide Free Ms WB
0.5 mg / €680.00
  Acris Antibodies GmbH

TRPV1 / Vanilloid receptor 1 (105-115) antibody

Western blot analysis of extracts from mouse brain using anti-TRPV1 rabbit whole antiserum. Rabbit Azide Free Ms WB
0.1 mg / €360.00
  Acris Antibodies GmbH

TRPV1 / Vanilloid receptor 1 antibody

TRPV1 / Vanilloid receptor 1 Rabbit Serum Rt C
50 µl / €540.00
  Acris Antibodies GmbH

TRPV1 / Vanilloid receptor 1 antibody

TRPV1 / Vanilloid receptor 1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

TRPV1 / Vanilloid receptor 1 antibody

TRPV1 / Vanilloid receptor 1 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

TRPV1 / Vanilloid receptor 1 antibody

Detection limit for recombinant GST tagged TRPV1 is approximately 0.03ng/ml as a capture antibody. Mouse IgG1 1F5 Purified Hu, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

TRPV1 / Vanilloid receptor 1 antibody

TRPV1 / Vanilloid receptor 1 Mouse IgG1 1F5 Ascites Hu, Rt E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

TRPV1 / Vanilloid receptor 1 antibody

TRPV1 / Vanilloid receptor 1 Mouse IgG2a 1A8 Purified Hu, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

TRPV1 / Vanilloid receptor 1 antibody

TRPV1 / Vanilloid receptor 1 Rabbit Hu, Ms, Rt C
0.1 ml / €390.00
  Abnova Taiwan Corp.

TRPV1 / Vanilloid receptor 1 antibody

Detection of TRPV1 in small neurons in rat dorsal root ganglion ( DRG ) using rabbit TRPV1 polyclonal antibody ( Cat # PAB0698 ) at 1 : 2000 dilution. Rabbit Hu, Rt C
0.1 ml / €390.00
  Abnova Taiwan Corp.

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