TRPV2 / VRL1 antibody

Principal name

TRPV2 / VRL1 antibody

Alternative names for TRPV2 / VRL1 antibody

VRL, OTRPC2, Vanilloid receptor-like protein 1, VRL-1, Transient receptor potential cation channel subfamily V member 2, Osm-9-like TRP channel 2

SwissProt ID

Q9WTR1 (Mouse), Q9WUD2 (Rat), Q9Y5S1 (Human)

Gene ID

51393 (TRPV2), 55503 (TRPV6), 22368 (Trpv2), 29465

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Gorilla, Eq (Equine), Hst (Hamster), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Goat, Mouse

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunohistochemistry (IHC)

Background of TRPV2 / VRL1 antibody

TRP channels are a large family (about 28 genes) of plasma membrane, non-selective cationic channels that are either specifically or ubiquitously expressed in excitable and non-excitable cells. The TRP channels have putative six-transmembrane domains (TM) with a pore domain between the fifth and the sixth TM, and all assemble as tetramers. Both the N- and the C-terminus of all TRPs are intracellular. According to IUPHAR, the TRP family is comprised of three main subfamilies on the basis of sequence homology; TRPC, TRPM and TRPV (to date, three additiol subfamilies are also considered to belong to the TRP family: the TRPA, TRPML, and TRPP). The TRPV subfamily consists of six members, TRPV1-6. Four members of the TRPV family have been described as a thermosensitive ion channels (TRPV1 to TRPV4). Each channel exhibits distinct thermal activation thresholds ranging from noxious cold (<17°C) to noxious heat (>52°C). Although it shares around 50% homology with TRPV1, TRPV2 is not activated by capsaicin nor by protons. It has a high temperature threshold of ~52°C and is considered to play an essential role in the perception of high-intensity noxious heat stimulation.The TRPV2 is also considered to be a stretch-activated channel and to play a role in skeletal and cardiac muscle degeneration and pain pathway. TRPV2 channel is expressed in DRG neurons, different brain region and non-neurol tissues such as spleen, lung and, intestine and in component of the immune system.

General readings

Saunders CI, Kunde DA, Crawford A, Geraghty DP.
Expression of transient receptor potential vanilloid 1 (TRPV1) and 2 (TRPV2) in human peripheral blood.
Mol Immunol. 2007 Feb;44(6):1429-35. Epub 2006 Jun 14. Erratum in: Mol Immunol.
PMID: 16777226

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TRPV2 / VRL1 (N-term) antibody

Anti-VRL1 / TRPV2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bov, Can, Eq, Hst, Hu, Mky, Ms, Por, Prim P
50 µg / €345.00
  OriGene Technologies, Inc.

TRPV2 / VRL1 antibody

Western blot analysis of ND7/23 cell line membrane (1,3), RBL lysates (2,4) and rat brain membrane (5,6): 1,2,5. Anti-TRPV2 (extracellular) antibody, (1:200). 3,4,6. Anti-TRPV2 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

TRPV2 / VRL1 (595-764) antibody

Human Small Intestine, submucosal plexus: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu, Ms P, WB
50 µl / €470.00
  Acris Antibodies GmbH

TRPV2 / VRL1 (C-term) antibody

TA303371 (2µg/ml) staining of Rat Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TRPV2 / VRL1 antibody

Anti-TRPV2 antibody IHC of human dorsal root ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Gorilla, Hu, Mky
50 µg / €345.00
  OriGene Technologies, Inc.

TRPV2 / VRL1 antibody

Anti-TRPV2 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Hu
50 µg / €345.00
  OriGene Technologies, Inc.

TRPV2 / VRL1 antibody

Western blot analysis of rat brain membrane (1,2) and RBL lysates (3,4): 1,3. Anti-TRPV2 antibody, (1:200). 2,4. Anti-TRPV2 antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

TRPV2 / VRL1 Control Peptide

TRPV2 / VRL1 Purified
50 µg / €220.00
  Acris Antibodies GmbH

TRPV2 / VRL1 antibody

TRPV2 / VRL1 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

TRPV2 / VRL1 antibody

Immunohistochemical staining of Trpv2 in rat dorsal horn using Trpv2 polyclonal antibody ( Cat # PAB14319 ). Rabbit Hu, Rt C, ICC/IF, WB
50 µg / €390.00
  Abnova Taiwan Corp.

TRPV2 / VRL1 antibody

TRPV2 / VRL1 Rabbit IgG Aff - Purified Hu P, WB
0.1 mg / €290.00
  Boster Immunoleader

TRPV2 / VRL1 antibody

TRPV2 / VRL1 Rabbit Aff - Purified Rt IHC
5 µg / €630.00
  Funakoshi Co., Ltd.

TRPV2 / VRL1 antibody

TRPV2 / VRL1 Rabbit Aff - Purified Hu P
50 µg / €440.00
  Novus Biologicals Inc.

TRPV2 / VRL1 antibody

NBP1-00139 (2ug/ml) staining of Rat Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

TRPV2 / VRL1 antibody

Western Blot:  VRL1 Antibody [NBP1-32096]- (30 µg of whole cell lysate) A:A431 B:Raji 7.5% SDS PAGE diluted at 1:500 Rabbit IgG Hu, Ms P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

TRPV2 / VRL1 antibody

Immunohistochemistry-Paraffin: VRL1 Antibody [NBP1-92576] - Immunohistochemical staining of human thyroid gland shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

TRPV2 overexpression lysate

TRPV2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

17 Item(s)

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