TRPV3 (Heat sensitive channel) antibody

Principal name

TRPV3 (Heat sensitive channel) antibody

SwissProt ID

Q4QYD9 (Rat)

Gene ID

497948

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Frozen Sections (C)

Background of TRPV3 (Heat sensitive channel) antibody

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces.
There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels; each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inward-rectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2).
The TRPV3 protein belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. The gene lies in close proximity to another family member (TRPV1) gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels (3, 4).

8 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TRPV3 (Heat sensitive channel) antibody

Western blot analysis of TrpV3 in a human cell line mix using a 1:1000 dilution of the antibody Mouse IgG2a S15-4 Purified Hu, Ms, Rt ICC/IF, IP, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TRPV3 (Heat sensitive channel) (458-474) antibody

Western blot analysis of TrpV3 in rat brain membrane lysates using a 1:1000 dilution of the antibody Mouse IgG2a S15-39 Purified Hu, Ms, Rt C, ICC/IF, IP, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TRPV3 (Heat sensitive channel) antibody

Transfected HEK293 cell immunofluorescence staining N15/4 TC supe =green, DAPI=blue Mouse IgG2a N15/4 Supernatant Hu, Ms, Rt ICC/IF, IP, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

TRPV3 (Heat sensitive channel) antibody

Transfected HEK293 cell immunofluorescence staining N15/39=green, DAPI=blue Mouse IgG1 N15/39 Supernatant Hu, Ms, Rt ICC/IF, IP, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

TRPV3 (Heat sensitive channel) antibody

Transfected HEK293 cell immunofluorescence staining N15/4 TC supe =green, DAPI=blue Mouse IgG2a N15/4 Purified Hu, Ms, Rt ICC/IF, IP, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

TRPV3 (Heat sensitive channel) antibody

Transfected HEK293 cell immunofluorescence staining N15/39=green, DAPI=blue Mouse IgG1 N15/39 Purified Hu, Ms, Rt ICC/IF, IP, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

TRPV3 (Heat sensitive channel) (C-term) antibody

Formalin-fixed and paraffin-embedded human testis tissue reacted with TRPV3 Antibody (C-term) (AP11389PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TRPV3 (Heat sensitive channel) antibody

Formalin-fixed and paraffin-embedded human testis tissue reacted with Trpv3 polyclonal antibody ( Cat # PAB3070 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

8 Item(s)

per page
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