TRRAP / PAF400 antibody

Principal name

TRRAP / PAF400 antibody

Alternative names for TRRAP / PAF400 antibody

Tra1 homolog, PAF350/400, STAF40, Transformation/transcription domain-associated protein, 350/400 kDa PCAF-associated factor

SwissProt ID

Q80YV3 (Mouse), Q9Y4A5 (Human)

Gene ID

8295 (TRRAP)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Immunoprecipitation (IP), PLA/Proximity ligation assay (PLA), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ChIP assay (ChIP)

Background of TRRAP / PAF400 antibody

TRRAP is an adapter protein, which is found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT), which gives a specific tag for epigenetic transcription activation. Plays a central role in MYC (c-Myc) transcription activation, and also participates in cell transformation by MYC. Required for TP53/p53-, E2F1- and E2F4-mediated transcription activation. Also involved in transcription activation mediated by the adenovirus E1A, a viral oncoprotein that deregulates transcription of key genes. Probably acts by linking transcription factors such as E1A, MYC or E2F1 to HAT complexes such as STAGA thereby allowing transcription activation. Probably not required in the steps following histone acetylation in processes of transcription activation. May be required for the mitotic checkpoint and normal cell cycle progression.

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Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TRRAP / PAF400

TRRAP / PAF400 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TRRAP / PAF400

TRRAP / PAF400 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

2 Item(s)

per page
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