Trypsin-3 / PRSS3 antibody

Principal name

Trypsin-3 / PRSS3 antibody

Alternative names for Trypsin-3 / PRSS3 antibody

PRSS4, TRY3, TRY4, Brain trypsinogen, Mesotrypsinogen, Serine protease 3, Serine protease 4, Trypsin III, Trypsin IV

SwissProt ID

P08426 (Rat), P35030 (Human), Q90629 (Chick)

Gene ID

5646 (PRSS3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of Trypsin-3 / PRSS3 antibody

The human pancreas secretes three different isoforms of the inactive trypsinogen into the small intestine, namely cationic trypsinogen, anionic trypsinogen (the two major isoforms) and mesotrypsinogen (a minor isoform). In the small intestine, each isoform is cleaved by Enterokinase into its active form, Trypsin-1, Trypsin-2 and Trypsin-3, respectively. All trypsins are members of the serine protease Trypsin family. The activated trypsins go on to activate other protease zymogens and play a role in the autoactivation of trypsinogens. This suggests an important role for trypsins in digestion. Mutations in the gene encoding Trypsin-1 that stimulate its activity are associated with autosomal dominant hereditary pancreatitis (HCP), also known as chronic pancreatitis (CP), a disease characterized by persistent, severe abdominal pain due to calcifications of the parenchyma, pancreatic stones, cysts and pancreatic head enlargement. Trypsin-3 is expressed in the brain in addition to the pancreas.

General readings

Jiang, G., et al. Gut 59(11):1535-1544 (2010).
Nakanishi, J., et al. J. Invest. Dermatol. 130(4):944-952 (2010).
Salameh, M.A., et al. J. Biol. Chem. 285(3):1939-1949 (2010).
Rosendahl, J., et al. Pancreatology 10 (2-3), 243-249 (2010).
Koistinen, H., et al. Neuroscience 160(1):97-102 (2009).

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Trypsin-3 / PRSS3 antibody

WB Suggested Anti-PRSS3 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Muscle Rabbit IgG Purified Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Trypsin-3 / PRSS3 antibody

Western blot (WB) analysis of Trypsin-3 antibody (Cat.-No.: AP20794PU-N) in extracts from A549 cells Rabbit Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Trypsin-3 / PRSS3 (Center) antibody

Formalin fixed and paraffin embedded human pancreas tissue reacted with RSS3 Antibody (Center) Cat.-No AP53469PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Trypsin-3 / PRSS3 (N-term) antibody

Immunohistochemistry analysis in human pancreas tissue (Formalin-fixed, Paraffin-embedded) using Trypsin-3 / PRSS3 antibody Cat.-No. AP53470PU-N (N-term), followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PRSS3 antibody for IHC; Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Trypsin-3 / PRSS3 (N-term) antibody

Human Muscle; WB Suggested Anti-PRSS3 Antibody Titration: 0.2-1 ug/ml. Positive Control: Human Muscle; PRSS3 antibody - N-terminal region (ARP56447_P050) in Human Muscle cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Trypsin-3 / PRSS3 antibody

Western blot analysis of Trypsin 3 expression in MDAMB231 (A); HL60 (B) whole cell lysates. Rabbit Aff - Purified Hu WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Trypsin-3 / PRSS3 antibody

Western blot analysis of Trypsin 3 expression in MDAMB231 (A); HL60 (B) whole cell lysates. Rabbit Aff - Purified Hu WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Trypsin-3 / PRSS3 antibody

Western blot analysis of Trypsin 3 expression in MDAMB231 (A); HL60 (B) whole cell lysates. Rabbit Aff - Purified Hu WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Trypsin-3 / PRSS3 antibody

Western Blot: PRSS3 Antibody [NBP1-57036] - This Anti-PRSS3 antibody was used in Western Blot of Fetal Muscle tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Trypsin-3 / PRSS3 (81-304, His-tag)

Trypsin-3 / PRSS3 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

Trypsin-3 / PRSS3 (81-304, His-tag)

Trypsin-3 / PRSS3 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Trypsin-3 / PRSS3 (81-304, His-tag)

Trypsin-3 / PRSS3 Human Purified > 95 % by SDS - PAGE Insect cells
0.25 mg / €940.00
  Acris Antibodies GmbH

Trypsin-3 / PRSS3 (81-304, His-tag)

Trypsin-3 / PRSS3 Human Purified > 95 % by SDS - PAGE Insect cells
50 µg / €300.00
  Acris Antibodies GmbH

Trypsin-3 / PRSS3

Trypsin-3 / PRSS3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue
10 µg / €380.00
  Abnova Taiwan Corp.

Trypsin-3 / PRSS3

Trypsin-3 / PRSS3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PRSS3 overexpression lysate

PRSS3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

PRSS3 overexpression lysate

PRSS3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

17 Item(s)

per page
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