Tryptase beta-1 (TPSAB1) antibody

Principal name

Tryptase beta-1 (TPSAB1) antibody

Alternative names for Tryptase beta-1 (TPSAB1) antibody

TPSB1, Tryptase I, Mast Cell Tryptase

SwissProt ID

P27435 (Rat), Q02844 (Mouse), Q15661 (Human)

Gene ID

7177 (TPSAB1), 17230 (Tpsab1), 100503895, 54271

Available reactivities

Hu (Human), Can (Canine), Fe (Feline), Mky (Monkey), Rt (Rat), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Tryptase beta-1 (TPSAB1) antibody

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteise inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mR stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha tryptases predomite. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.

General readings

Tanaka T. et al. (1983) J Biol Chem. 258(22):13552-7.Marquardt U. et al. (2002) J Mol Biol. 321(3):491-502.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Tryptase beta-1 (TPSAB1) antibody

  Mouse Monoclonal Tryptase Antibody  
Immunohistochemistry staining of Paraffin Uterus tissue by Tryptase antibody (dilution: 1:200 - 1:1000; visualization of staining: Cytoplasmic) Mouse IgG1 G3 Purified Hu P
1 ml / €425.00
  OriGene Technologies, Inc.

Tryptase beta-1 (TPSAB1) antibody

  Rabbit anti-TPSAB1 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using TPSAB1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Tryptase beta-1 (TPSAB1) antibody

Formalin-Fixed, Paraffin-Embedded Human neurofibroma stained with Tryptase antibody Cat.-No. AM10146SU-N using peroxidase conjugate and DAB chromogen. Note the cytoplasmic staining of mast cells. Mouse IgG1 G3 Supernatant Hu P
1 ml / €290.00
  Acris Antibodies GmbH

Tryptase beta-1 (TPSAB1) antibody

Staining of Human Tonsil with Mouse anti Human Mast Cell Tryptase Antibody (SM1220P/PT) Mouse IgG1 AA1 Purified Can, Fe, Hu, Mky, Rt C, E, ICC/IF, P, WB
0.2 mg / €520.00
  Acris Antibodies GmbH

Tryptase beta-1 (TPSAB1) antibody

Staining of Human Tonsil with Mouse anti Human Mast Cell Tryptase Antibody (SM1220P/PT) Mouse IgG1 AA1 Purified Can, Fe, Hu, Mky, Rt C, E, P, WB
20 µg / €200.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

TPSAB1 - human gene knockout kit via CRISPR

TPSAB1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

TPSAB1 - human gene knockout kit via CRISPR

TPSAB1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

TPSAB1 - human gene knockout kit via CRISPR

TPSAB1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

TPSAB1 - human gene knockout kit via CRISPR

TPSAB1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tpsab1 - mouse gene knockout kit via CRISPR

Tpsab1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Tpsab1 - mouse gene knockout kit via CRISPR

Tpsab1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tpsab1 - mouse gene knockout kit via CRISPR

Tpsab1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tpsab1 - mouse gene knockout kit via CRISPR

Tpsab1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Tryptase beta-1 (TPSAB1) (31-275, His-tag)

Tryptase beta-1 (TPSAB1) Human Purified > 85 % by SDS - PAGE E. coli
0.25 mg / €730.00
  Acris Antibodies GmbH

Tryptase beta-1 (TPSAB1) (31-275, His-tag)

Tryptase beta-1 (TPSAB1) Human Purified > 85 % by SDS - PAGE E. coli
50 µg / €300.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TPSAB1 (mGFP-tagged) - Human tryptase alpha/beta 1 (TPSAB1), 200 uL, >10^7 TU/mL

Lenti ORF particles, TPSAB1 (mGFP-tagged) - Human tryptase alpha/beta 1 (TPSAB1), 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, TPSAB1 (Myc-DDK tagged) - Human tryptase alpha/beta 1 (TPSAB1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, TPSAB1 (Myc-DDK tagged) - Human tryptase alpha/beta 1 (TPSAB1) , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tpsab1 (GFP-tagged) - Mouse tryptase alpha/beta 1 (Tpsab1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Tpsab1 (GFP-tagged) - Mouse tryptase alpha/beta 1 (Tpsab1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tpsab1 (Myc-DDK-tagged) - Mouse tryptase alpha/beta 1 (Tpsab1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Tpsab1 (Myc-DDK-tagged) - Mouse tryptase alpha/beta 1 (Tpsab1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tpsab1 (GFP-tagged ORF) - Rat tryptase alpha/beta 1 (Tpsab1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tpsab1 (GFP-tagged ORF) - Rat tryptase alpha/beta 1 (Tpsab1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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