TSC2 / Tuberin antibody

Principal name

TSC2 / Tuberin antibody

Alternative names for TSC2 / Tuberin antibody

Tuberous sclerosis 2 protein, TSC4

SwissProt ID

A7E2E2 (Human)

Gene ID

7249 (TSC2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C), Dot blot (Dot)

Background of TSC2 / Tuberin antibody

Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder that is caused by mutation in either the TSC1 (hamartin) or TSC2 (tuberin) gene. TSC1 and TSC2 proteins form a physical and functional heterodimer in vivo that inhibits ribosomal protein S6 kinase 1 (S6K1) and activates eukaryotic initiation factor 4E-binding protein 1 (4E-BP1) by inhibition of the mammalian target of rapamycin (mTOR). TSC2 belongs to small GTPase protein of the Ras superfamily, contain a Rap-GAP domain. Predicted molecular weight 201 kD. TSC2 is directly phosphorylated and inhibited by Akt that is involved in stimulating cell growth and is activated by growth stimulating signals, such as insulin. Thr1462 of TSC2 is Akt-regulated phosphorylation site. The Poly6358 antibody recognizes human phospho-TSC2 (Thr1462) and has been shown to be useful for immunoflorence staining. This antibody does not detect TSC2 phosphorylated at other sites.

15 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TSC2 / Tuberin antibody

TSC2 / Tuberin Mouse IgG1 1C1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

TSC2 / Tuberin pSer939 antibody

Dot blot analysis of TSC2 (phospho S939) polyclonal antibody ( Cat # PAB8093 ) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/ml. Rabbit Hu Dot, E
0.4 ml / €400.00
  Abnova Taiwan Corp.

TSC2 / Tuberin pSer664 antibody

Dot blot analysis of TSC2 (phospho S664) polyclonal antibody ( Cat # PAB8108 ) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/ml. Rabbit Hu Dot, E
0.4 ml / €400.00
  Abnova Taiwan Corp.

TSC2 / Tuberin pSer1798 antibody

Dot blot analysis of TSC2 (phospho S1798) polyclonal antibody ( Cat # PAB8151 ) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/ml. Rabbit Hu Dot, E
0.4 ml / €400.00
  Abnova Taiwan Corp.

TSC2 / Tuberin pSer1420 antibody

Dot blot analysis of TSC2 (phospho S1420) polyclonal antibody ( Cat # PAB8152 ) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/ml. Rabbit Hu Dot, E
0.4 ml / €400.00
  Abnova Taiwan Corp.

TSC2 / Tuberin antibody

Western blot analysis of TSC2 in L1210 cell lysate with TSC2 polyclonal antibody ( Cat # PAB13146 ) at 1 µg/ml in the ( A ) absence and ( B ) presence of blocking peptide. Rabbit Hu, Ms WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

TSC2 / Tuberin antibody

Immunocytochemistry of TSC2 in L1210 cells with TSC2 polyclonal antibody ( Cat # PAB13147 ) at 10 µg/ml. Rabbit Hu, Ms ICC/IF, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

TSC2 / Tuberin antibody

Immunohistochemistry: Tuberin/TSC2 Antibody [NB100-92235] - Immunohistochemistry (IHC) analyzes of  Tuberin/TSC2 (F933) antibody in paraffin-embedded  humanlung carcinoma tissue Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

TSC2 / Tuberin antibody

TSC2 / Tuberin Rabbit IgG Aff - Purified Hu, Ms, Rt P
0.1 mg / €420.00
  Novus Biologicals Inc.

TSC2 / Tuberin antibody

TSC2 / Tuberin Rabbit Aff - Purified Hu P
0.1 mg / €420.00
  Novus Biologicals Inc.

TSC2 / Tuberin antibody

TSC2 / Tuberin Rabbit Aff - Purified Hu, Ms, Rt P
0.1 mg / €420.00
  Novus Biologicals Inc.

TSC2 / Tuberin pSer939 antibody

TSC2 / Tuberin Rabbit Hu, Ms, Rt E, P, WB
50 µg / €360.00
  Novus Biologicals Inc.

TSC2 / Tuberin pSer939 antibody

TSC2 / Tuberin Rabbit Hu, Ms, Rt C, E, WB
0.1 mg / €480.00
  Novus Biologicals Inc.

TSC2 / Tuberin pThr1462 antibody

TSC2 / Tuberin Rabbit Hu, Ms, Rt E, P, WB
50 µg / €360.00
  Novus Biologicals Inc.

TSC2 / Tuberin pThr1462 antibody

TSC2 / Tuberin Rabbit Hu, Ms, Rt C, E, WB
0.1 mg / €480.00
  Novus Biologicals Inc.

15 Item(s)

per page
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