TSG101 antibody

Principal name

TSG101 antibody

Alternative names for TSG101 antibody

Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101

SwissProt ID

Q61187 (Mouse), Q6IRE4 (Rat), Q99816 (Human)

Gene ID

7251 (TSG101), 22088 (Tsg101), 292925

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Dros (Drosophila), Eq (Equine), GP (Guinea Pig), Gt (Goat), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of TSG101 antibody

TSG101 belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. TSG101 contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. TSG101 may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of TSG101 appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in TSG101 gene occur in high frequency in breast cancer. The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

General readings

Vardhana S., et al. (2010) Immunity. 32(4):531-40.
Popov S., et al. (2009) J Virol. 83(14):7185-93.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TSG101 antibody

  Rabbit Polyclonal Anti-TSG101 Antibody  
Sample Type: mouse fibroblast lusate (10 ug); Primary Dilution: 1:1000 (1% BSA); Secondary Dilution: 1:2000 (5% milk); Image Submitted By: Anonymous researcher See Customer Feedback tab for detailed information. Rabbit IgG Purified Ms P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TSG101 (201-281) antibody

Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a 5B7 Purified Hu E, ICC/IF, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

TSG101 antibody

  Rabbit polyclonal anti-TSG101 antibody  
Western blot analysis of extracts from COS-7 cells, using TS101 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TSG101 antibody

  Rabbit Polyclonal Anti-TSG101 Antibody  
Host: Rabbit; Target Name: TSG101; Sample Tissue: Thymus tumor lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

TSG101 antibody

  Rabbit Polyclonal Anti-TSG101 Antibody  
WB Suggested Anti-TSG101 Antibody Titration: 2.5 ug/ml; ELISA Titer: 1: 312500; Positive Control: HepG2 cell lysate; TSG101 is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TSG101 (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TSG101 (C-term) antibody

Western Blot Analysis of anti-TSG101 (C-term) Pab (Cat.#AP12056PU-N) to detect TSG101 in ZR75-1 cell lysate. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TSG101 antibody

Immunohistochemistry (IHC) analyzes of Tsg 101 antibody (Cat.-No.: AP20455PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Tsg101 - mouse gene knockout kit via CRISPR

Tsg101 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tsg101 - mouse gene knockout kit via CRISPR

Tsg101 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tsg101 - mouse gene knockout kit via CRISPR

Tsg101 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TSG101 (full length, C-term DDK tag)

  Recombinant protein of human human tumor susceptibility gene 101 (TSG101), full length, with C-terminal DDK tag, expressed in sf9 cells  
TSG101 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

TSG101 (1-145, His-tag)

TSG101 Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €1,000.00
  Acris Antibodies GmbH

TSG101 (1-145, His-tag)

TSG101 Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

TSG101 overexpression lysate

TSG101 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TSG101 (mGFP-tagged) - Human tumor susceptibility gene 101 (TSG101), 200 uL, >10^7 TU/mL

Lenti ORF particles, TSG101 (mGFP-tagged) - Human tumor susceptibility gene 101 (TSG101), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, TSG101 (Myc-DDK tagged) - Human tumor susceptibility gene 101 (TSG101) , 200 uL, >10^7 TU/mL

Lenti ORF particles, TSG101 (Myc-DDK tagged) - Human tumor susceptibility gene 101 (TSG101) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tsg101 (GFP-tagged) - Mouse tumor susceptibility gene 101 (Tsg101), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tsg101 (GFP-tagged) - Mouse tumor susceptibility gene 101 (Tsg101), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Tsg101 (Myc-DDK-tagged) - Mouse tumor susceptibility gene 101 (Tsg101), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tsg101 (Myc-DDK-tagged) - Mouse tumor susceptibility gene 101 (Tsg101), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tsg101 (GFP-tagged ORF) - Rat tumor susceptibility gene 101 (Tsg101), 200 uL, >10^7 TU/mL

Lenti ORF particles, Tsg101 (GFP-tagged ORF) - Rat tumor susceptibility gene 101 (Tsg101), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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