TSHZ3 / ZNF537 antibody

Principal name

TSHZ3 / ZNF537 antibody

Alternative names for TSHZ3 / ZNF537 antibody

Zinc finger protein 537, Teashirt homolog 3, TSH3, KIAA1474

SwissProt ID

D3ZKB9, Q63HK5 (Human), Q8CGV9 (Mouse)

Gene ID

57616 (TSHZ3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of TSHZ3 / ZNF537 antibody

TSHZ3 is a transcriptional regulator involved in developmental processes. It function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. TSHZ3 associates with chromatin in a region surrounding the CASP4 transcriptional start site(s) and regulates the development of neurons involved in both respiratory rhythm and airflow control. It promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator (RRG) activity compatible with survival at birth. TSHZ3 ot ZNF537 is involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes and in the up-regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter.

General readings

"FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4." Kajiwara Y., Akram A., Katsel P., Haroutunian V., Schmeidler J., Beecham G., Haines J.L., Pericak-Vance M.A., Buxbaum J.D. PLoS ONE 4:E5071-E5071(2009)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TSHZ3 / ZNF537 (N-term) antibody

TSHZ3 / ZNF537 Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TSHZ3 / ZNF537 antibody

TSHZ3 / ZNF537 Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

TSHZ3 / ZNF537 (N-term) Control Peptide

TSHZ3 / ZNF537
50 µg / €160.00
  Acris Antibodies GmbH

TSHZ3 / ZNF537 antibody

TSHZ3 / ZNF537 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

TSHZ3 / ZNF537 antibody

TSHZ3 / ZNF537 Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

TSHZ3 / ZNF537 antibody

TSHZ3 / ZNF537 Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TSHZ3 / ZNF537

TSHZ3 / ZNF537 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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