TTBK1 antibody

Principal name

TTBK1 antibody

Alternative names for TTBK1 antibody

Tau-tubulin kinase 1, Brain-derived tau kinase, BDTK, KIAA1855

SwissProt ID

Q5TCY1 (Human), Q6PCN3 (Mouse)

Gene ID

84630 (TTBK1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of TTBK1 antibody

TTBK1 (tau tubulin kinase 1), also known as BDTK (brain-derived tau kinase), is a 1,321 amino acid protein that contains one protein kinase domain and belongs to the serine/threonine protein kinase family. Localized to the cytoplasm and expressed at high levels in brain and at lower levels in testis and spinal cord, TTBK1 functions as a serine/threonine kinase that can phosphorylate Tau (a protein involved in tubulin polymerization) on threonine, tyrosine and serine residues. Specifically, TTBK1 uses divalent cations, such as magnesium and manganese, to catalyze the ATP-dependent transfer of a phosphate group onto Tau, creating a phosphoprotein and ADP. Phosphorylation of Tau causes its aggregation and subsequent loss of function, suggesting an important role for TTBK1 in the control of tubulin dynamics. Two isoforms of TTBK1 are expressed due to alternative splicing events.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TTBK1 antibody

Western blot analysis of TTBK1 in Jurkat lysate with TTBK1 antibody at 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TTBK1 (C-term) antibody

Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

TTBK1 Control Peptide

TTBK1
50 µg / €160.00
  Acris Antibodies GmbH

TTBK1 antibody

TTBK1 Rabbit Aff - Purified Hu, Ms E, P, WB
50 µg / €480.00
  Novus Biologicals Inc.

TTBK1 antibody

Immunohistochemistry-Paraffin: TTBK1 Antibody [NBP1-76989] - Mouse brain tissue with TTBK1 antibody at 2.5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

TTBK1 antibody

Immunohistochemistry-Paraffin: TTBK1 Antibody [NBP1-82888] - Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in purkinje cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TTBK1

TTBK1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

TTBK1

TTBK1 Human
5 µg / €610.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

TTBK1 overexpression lysate

TTBK1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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