Home » Target » TTC1 / TPR1 antibody

TTC1 / TPR1 antibody

Principal name

TTC1 / TPR1 antibody

Alternative names for TTC1 / TPR1 antibody

Tetratricopeptide repeat protein 1, TPR repeat protein 1

SwissProt ID

Q3ZBR5 (Bovin), Q91Z38 (Mouse), Q99614 (Human)

Gene ID

7265 (TTC1), 66827 (Ttc1)

Ncbi ID

9606, NP_003305, NP_003305.1, NM_133795

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), EPair for Elisa (EPair), Immunoprecipitation (IP)

Background of TTC1 / TPR1 antibody

TTC1, also known as tetratricopeptide repeat protein 1, is composed of 292 amino acids with three TPR motifs, as a Galpha16-binding protein. The interaction was confirmed both in vitro and in transfected mammalian cells, where TTC1 also binds to several other Galpha proteins. TTC1 was found to interact with Ha-Ras preferentially in its active form.

General readings

Liu AM., et al. (2011) BMC Struct Biol. 13;11:17Strausberg RL., et al. (2007) Proc. Natl. Acad. Sci. U.S.A. 26:16899-16903

Immunoperoxidase of monoclonal antibody to TTC1 on formalin-fixed paraffin-embedded human liver. [antibody concentration 1.5 ug/ml]

H00007265-M01

Immunofluorescence of purified MaxPab antibody to TTC1 on HeLa cell. [antibody concentration 10 ug/ml]

H00007265-B01P

Western Blot analysis of TTC1 expression in transfected 293T cell line (H00007265-T01) by TTC1 MaxPab polyclonal antibody.Lane 1: TTC1 transfected lysate(32.12 KDa).Lane 2: Non-transfected lysate.

H00007265-B01P

TTC1 MaxPab polyclonal antibody. Western Blot analysis of TTC1 expression in Jurkat.

H00007265-B01P

Western Blot analysis of TTC1 expression in transfected 293T cell line (H00007265-T01) by TTC1 MaxPab polyclonal antibody.Lane 1: TTC1 transfected lysate(33.50 KDa).Lane 2: Non-transfected lysate.

H00007265-D01P

Western Blot analysis of TTC1 expression in transfected 293T cell line (H00007265-T01) by TTC1 MaxPab polyclonal antibody.Lane 1: TTC1 transfected lysate(33.50 KDa).Lane 2: Non-transfected lysate.

H00007265-D01

Immunoprecipitation of TTC1 transfected lysate using anti-TTC1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with TTC1 MaxPab mouse polyclonal antibody (B01) (H00007265-B01).