TTC3 / RNF105 antibody

Principal name

TTC3 / RNF105 antibody

Alternative names for TTC3 / RNF105 antibody

DCRR1, TPRD, Tetratricopeptide repeat protein 3, TPR repeat protein 3, TPR repeat protein D, RING finger protein 105

SwissProt ID

P53804 (Human)

Gene ID

7267 (TTC3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C)

Background of TTC3 / RNF105 antibody

E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation; its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TTC3 / RNF105 antibody

TTC3 / RNF105 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

TTC3 / RNF105 antibody

TTC3 / RNF105 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

TTC3 / RNF105 antibody

Detection limit for recombinant GST tagged TTC3 is approximately 1ng/ml as a capture antibody. Mouse IgG2a 2D10 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

TTC3 / RNF105 antibody

Immunohistochemistry-Paraffin: TTC3 Antibody [NBP1-84292] - Immunohistochemical staining of human liver shows moderate cytoplasmic positivity in hepatocytes. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

TTC3 / RNF105 antibody

Immunohistochemistry-Paraffin: TTC3 Antibody [NBP1-84293] Immunohistochemical staining of human kidney shows strong cytoplasmic and nuclear positivity in tubular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TTC3 / RNF105

TTC3 / RNF105 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TTC3 / RNF105

TTC3 / RNF105 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

TTC3 overexpression lysate

TTC3 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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