TTC8 / BBS8 antibody

Principal name

TTC8 / BBS8 antibody

Alternative names for TTC8 / BBS8 antibody

TPR repeat protein 8, Bardet-Biedl syndrome 8 protein, Tetratricopeptide repeat protein 8

SwissProt ID

Q8TAM2 (Human), Q8VD72 (Mouse)

Gene ID

123016 (TTC8)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Bov (Bovine), Por (Porcine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of TTC8 / BBS8 antibody

The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. Alternate transcriptional splice variants have been characterized.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TTC8 / BBS8 antibody

(0.2ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TTC8 / BBS8 antibody

WB Suggested Anti-TTC8 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

TTC8 / BBS8 (N-term) antibody

TTC8 Antibody (N-term) (AP54402PU-N) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the TTC8 antibody detected the TTC8 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TTC8 / BBS8 antibody

TTC8 / BBS8 Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

TTC8 / BBS8 antibody

Human THP-1; WB Suggested Anti-TTC8 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: THP-1 cell lysate; TTC8 antibody - N-terminal region (ARP49176_P050) in Human THP-1 cells using Western Blot Rabbit Aff - Purified Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TTC8 / BBS8 (transcript variant 2)

TTC8 / BBS8 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Antibody Pairs

Catalog No.    

TTC8 (Human) IP-WB Antibody Pair

TTC8 (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

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