TUSC4 / NPRL2 antibody

Principal name

TUSC4 / NPRL2 antibody

Alternative names for TUSC4 / NPRL2 antibody

NPR2-like, Tumor suppressor candidate 4, Gene 21 protein

SwissProt ID

Q5E9U9 (Bovin), Q8WTW4 (Human), Q9WUE4 (Mouse)

Gene ID

10641 (NPRL2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Ze (Zebrafish), African clawed frog, Xen (Xenopus), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Eq (Equine)

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of TUSC4 / NPRL2 antibody

TUSC4 suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream sigling. TUSC4 down-regulates PDPK1 kise activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. TUSC4 may act as a tumor suppressor. TUSC4 suppresses cell growth and enhanced sensitivity to various anticancer drugs.

General readings

Ueda K, Kawashima H, Ohtani S, Deng WG, Ravoori M, Bankson J, Gao B, Girard L, Minna JD, Roth JA, Kundra V, Ji L.
The 3p21.3 tumor suppressor NPRL2 plays an important role in cisplatin-induced resistance in human non-small-cell lung cancer cells.
Cancer Res. 2006 Oct 1;66(19):9682-90.
PMID: 17018626

18 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TUSC4 / NPRL2 (140-151) antibody

TA303320 (0.1µg/ml) staining of Human Muscle lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TUSC4 / NPRL2 antibody

Western blot analysis of extracts of various cell lines, using NPRL2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

TUSC4 / NPRL2 antibody

WB Suggested Anti-NPRL2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: OVCAR-3 cell lysate NPRL2 is supported by BioGPS gene expression data to be expressed in OVCAR3 Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Por, Rb, Rt, Ze P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

TUSC4 / NPRL2 antibody

WB Suggested Anti-NPRL2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: NCI-H226 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

TUSC4 / NPRL2 (C-term) antibody

NPRL2 Antibody (C-term) (Cat. #AP52920PU-N) western blot analysis in HL-60 cell line lysates (35µg/lane).This demonstrates the NPRL2 antibody detected the NPRL2 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TUSC4 / NPRL2 antibody

Immunofluorescence of purified MaxPab antibody to TUSC4 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu, Ms E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

TUSC4 / NPRL2 antibody

Immunofluorescence of purified MaxPab antibody to TUSC4 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

TUSC4 / NPRL2 antibody

TUSC4 polyclonal antibody ( Cat # PAB7434 ) ( 0.1 µg/ml ) staining of human muscle lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

TUSC4 / NPRL2 antibody

Human Adult Liver; Rabbit Anti-TUSC4 Antibody . Catalog Number: ARP50539_P050. Formalin Fixed Paraffin Embedded Tissue: Human Adult Liver . Observed Staining: Cytoplasm in hepatocytes, moderate signal, very low tissue distribution. Primary Antibody Concentration: 1:100. Secondary Antibody: Donkey anti-Rabbit-Cy3. Secondary Antibody Concentration: 1:200. Magnification: 20X. Exposure Time: 0.5 – 2.0 sec. Protocol located in Reviews and Data.; TUSC4 antibody - N-terminal region (ARP50539_P050) in Human Adult Liver cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

TUSC4 / NPRL2 antibody

Human NCI-H226; WB Suggested Anti-TUSC4 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: NCI-H226 cell lysate; TUSC4 antibody - middle region (ARP50540_P050) in Human NCI-H226 cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

TUSC4 / NPRL2 antibody

NB100-93442 (0.1ug/ml) staining of Human Muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

TUSC4 / NPRL2 antibody

TUSC4 / NPRL2 Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt, Xen, Ze WB
50 µg / €440.00
  Novus Biologicals Inc.

TUSC4 / NPRL2 antibody

TUSC4 / NPRL2 Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TUSC4 / NPRL2

TUSC4 / NPRL2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TUSC4 / NPRL2

TUSC4 / NPRL2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

NPR2L 293T Cell Transient Overexpression Lysate(Denatured)

NPR2L 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

TUSC4 Lysate(Denatured)

TUSC4 Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

NPRL2 overexpression lysate

NPRL2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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