TWEAK / TNFSF12 antibody

Principal name

TWEAK / TNFSF12 antibody

Alternative names for TWEAK / TNFSF12 antibody

APO3 ligand, APO3L, DR3LG, Tumor necrosis factor ligand superfamily member 12, TNF-related weak inducer of apoptosis

SwissProt ID

O43508 (Human), O54907 (Mouse)

Gene ID

8742 (TNFSF12), 21944 (Tnfsf12), 407977

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Eq (Equine), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Goat, Mouse, Rat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Functional assay (FN), Flow Cytometry (F), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of TWEAK / TNFSF12 antibody

TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Jin,L., et al., (2004) J. Invest. Dermatol. 122 (5), 1175-1179

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TWEAK / TNFSF12 antibody

Western blot analysis of (A) 5 ng, (B) 25 ng and (C) 50 ng of recombinant TWEAK with TWEAK antibody at 1 ug/ml. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TWEAK / TNFSF12 antibody

Western blot analysis of extracts from COLO cells, HUVEC cells and 293 cells, using TNF12 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TWEAK / TNFSF12 antibody

TWEAK / TNFSF12 Mouse CARL-2 Purified Hu E
25 µg / €120.00
  OriGene Technologies, Inc.

TWEAK / TNFSF12 antibody

To detect hTWEAK by direct ELISA (using 100 ul/well antibody solution) a concentration of 0.25-1.0 ug/ml of this antibody is required.  This biotinylated polyclonal antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2-0.4 ng/well of recombinant hTWEAK. Goat IgG Purified Hu E, WB
50 µg / €325.00
  OriGene Technologies, Inc.

TWEAK / TNFSF12 antibody

To detect hTWEAK by sandwich ELISA (using 100 ul/well antibody solution) a concentration of 0.5 - 2.0 ug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Human TWEAK (TA328466) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hTWEAK. Goat IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TWEAK / TNFSF12 antibody

WB Suggested Anti-TNFSF12 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: Human muscle Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

TWEAK / TNFSF12 antibody

Western blot analysis of extracts of various cell lines, using TNFSF12 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

TWEAK / TNFSF12 antibody

WB Suggested Anti-TNFSF12 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: 721_B cell lysate Rabbit IgG Purified Can, Eq, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

TWEAK / TNFSF12 antibody

Western blot analysis on HuvEc,Jurkat and 293 cell lysate using TNFSF12 Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TWEAK / TNFSF12 antibody

TWEAK / TNFSF12 Mouse IgG3 CARL-1 Low Endotoxin Hu F, FN
0.1 mg / €210.00
  Acris Antibodies GmbH

TWEAK / TNFSF12 antibody

TWEAK / TNFSF12 Mouse IgG3 CARL-1 Purified Hu F, FN
0.1 mg / €210.00
  Acris Antibodies GmbH

TWEAK / TNFSF12 antibody

TWEAK / TNFSF12 Mouse IgG3 CARL-1 PE Hu F
100 Tests / €290.00
  Acris Antibodies GmbH

TWEAK / TNFSF12 antibody

Immunohistochemistry (IHC) analyzes of TWEAK antibody (Cat.-No.: AP20513PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

TWEAK / TNFSF12 antibody

TWEAK / TNFSF12 Goat Biotin Hu E, WB
25 µg / €230.00
  Acris Antibodies GmbH

TWEAK / TNFSF12 antibody

TWEAK / TNFSF12 Goat Biotin Hu E, WB
50 µg / €340.00
  Acris Antibodies GmbH

TWEAK / TNFSF12 antibody

TWEAK / TNFSF12 Goat Aff - Purified Hu E, FN, WB
50 µg / €230.00
  Acris Antibodies GmbH

TWEAK / TNFSF12 antibody

TWEAK / TNFSF12 Goat Aff - Purified Hu E, FN, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

TWEAK / TNFSF12 antibody

Western Blot analysis of TNFSF12 expression in transfected 293T cell line (H00008742-T01) by TNFSF12 MaxPab polyclonal antibody.

Lane 1: TNFSF12 transfected lysate(14.74 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

TWEAK / TNFSF12 antibody

Western Blot analysis of TNFSF12 expression in transfected 293T cell line (H00008742-T01) by TNFSF12 MaxPab polyclonal antibody.

Lane 1: TNFSF12 transfected lysate(14.74 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

TWEAK / TNFSF12 antibody

Detection limit for recombinant GST tagged TNFSF12 is approximately 0.03ng/ml as a capture antibody. Mouse IgG2a 4H3 Purified Hu, Ms E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

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