TXK / PTK4 antibody

Principal name

TXK / PTK4 antibody

Alternative names for TXK / PTK4 antibody

Tyrosine-protein kinase TXK, Protein-tyrosine kinase 4

SwissProt ID

P42681 (Human), P42682 (Mouse)

Gene ID

7294 (TXK)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of TXK / PTK4 antibody

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

General readings

1. Suzuki N, Nara K, Suzuki T. Skewed Th1 responses caused by excessive expression of Txk, a member of the Tec family of tyrosine kinases, in patients with Behcet's disease.
Clin Med Res. 2006 Jun;4(2):147-51. Review. PMID: 16809408

8 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TXK / PTK4 (C-term) antibody

  Goat Anti-TXK Antibody  
(2ug/ml) staining of Human Tonsil lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TXK / PTK4 (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

TXK - human gene knockout kit via CRISPR

TXK - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

TXK - human gene knockout kit via CRISPR

TXK - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

TXK - human gene knockout kit via CRISPR

TXK - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

TXK - human gene knockout kit via CRISPR

TXK - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TXK (mGFP-tagged)-Human TXK tyrosine kinase (TXK), 200 uL, >10^7 TU/mL

Lenti ORF particles, TXK (mGFP-tagged)-Human TXK tyrosine kinase (TXK), 200 uL, >10^7 TU/mL  
200 µl / €1,150.00
  OriGene Technologies, Inc.

Lenti ORF particles, TXK (Myc-DDK-tagged)-Human TXK tyrosine kinase (TXK), 200 uL, >10^7 TU/mL

Lenti ORF particles, TXK (Myc-DDK-tagged)-Human TXK tyrosine kinase (TXK), 200 uL, >10^7 TU/mL  
200 µl / €1,030.00
  OriGene Technologies, Inc.

8 Item(s)

per page
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