TXNIP / VDUP1 antibody

Principal name

TXNIP / VDUP1 antibody

Alternative names for TXNIP / VDUP1 antibody

Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1, Thioredoxin-binding protein 2

SwissProt ID

Q2HY40 (Pig), Q5M7W1 (Rat), Q8BG60 (Mouse), Q9H3M7 (Human)

Gene ID

10628 (TXNIP)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), African clawed frog, Sh (Sheep), Xen (Xenopus), Prim (Primate), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Enzyme Immunoassay (E)

Background of TXNIP / VDUP1 antibody

Thioredoxin-interacting protein (TXNIP) belongs to the arrestin family and plays a critical role in the antioxidant defense mechanisms of hematopoietic cells by activating the p53 pathway during oxidative stress (1,2). It functions as a transcriptiol repressor and acts as an oxidative stress mediator by inhibiting thioredoxin activity (2). TXNIP expression is reduced in many types of tumors, and TXNIP overexpression inhibits tumor growth by blocking cell-cycle progression (3). It has recently reported that TXNIP deficiency correlates with a high incidence of hepatocellular carcinoma (HCC) (4). TXNIP and p53 interactions could potentially be a therapeutic target for oxidative stress-related diseases such as hematopoietic maligncies and metabolic diseases (5).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TXNIP / VDUP1 antibody

Western Blot: TXNIP Antibody [TA337136] - Analysis of TxNIP in Raji cell lysate in the 1) absence and 2) presence of immunizing peptide using this antibody. goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this Rabbit Purified Hu, Prim WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TXNIP / VDUP1 antibody

WB Suggested Anti-TXNIP Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human heart Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rb, Rt, Sh WB
50 µg / €325.00
  OriGene Technologies, Inc.

TXNIP / VDUP1 antibody

Western blot analysis of TXNIP in C2C12 cell lysate with TXNIP antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TXNIP / VDUP1 antibody

Western blot analysis of VDUP-1 expression in Raji cells (Lane 1), K562 cells (Lane 2), KG1 cells (Lane 3), MRC5  cells (Lane 4), IC2Tr cells (Lane 5), HEL cells (Lane 6) and P19 cells (Lane 7) using AM20295AF-N VDUP-1 antibody Mouse IgG2b JY1 Azide Free Hu, Ms IP, WB
0.1 mg / €410.00
  Acris Antibodies GmbH

TXNIP / VDUP1 antibody

Western blot analysis of Txnip/VDUP1 expression in Raji (1), K562 (Lane 2), KG1 (Lane 3), MRC5 (Lane 4), IC2Tr (Lane 5), HEL (Lane 6), P19 (Lane 7) and WR19L (Lane 8) using AM20296AF-N. Mouse IgG1 JY2 Azide Free Hu, Ms, Rt IP, P, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

TXNIP / VDUP1 antibody

Hum. Adult Placenta; Host: Rabbit . Target Name: TXNIP . Sample Tissue: Human Adult Placenta . Antibody Dilution: 1.0ug/ml.; TXNIP antibody - C-terminal region (ARP52193_P050) in Hum. Adult Placenta cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Por, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

TXNIP / VDUP1 antibody

TXNIP / VDUP1 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

TXNIP / VDUP1 antibody

Western Blot: TXNIP Antibody [NBP1-52909] - This Anti-TXNIP antibody was used in Western Blot of Fetal Heart tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt, Sh, Xen WB
50 µg / €440.00
  Novus Biologicals Inc.

TXNIP / VDUP1 antibody

TXNIP / VDUP1 Mouse IgG1 JY2 Purified Hu, Ms, Rt C, F, ICC/IF, IP, WB
50 µg / €360.00
  Novus Biologicals Inc.

TXNIP / VDUP1 antibody

Immunohistochemistry-Paraffin: TXNIP Antibody [NBP1-84784] Immunohistochemical staining of human cervix, uterine shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TXNIP / VDUP1

TXNIP / VDUP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

TXNIP / VDUP1

TXNIP / VDUP1 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

TXNIP / VDUP1

TXNIP / VDUP1 Human
10 µg / €380.00
  Abnova Taiwan Corp.

13 Item(s)

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