TXNIP / VDUP1 antibody
Principal name
TXNIP / VDUP1 antibody
Alternative names for TXNIP / VDUP1 antibody
Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1, Thioredoxin-binding protein 2
Gene ID
10628 (TXNIP)
Ncbi ID
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Enzyme Immunoassay (E)
Background of TXNIP / VDUP1 antibody
Thioredoxin-interacting protein (TXNIP) belongs to the arrestin family and plays a critical role in the antioxidant defense mechanisms of hematopoietic cells by activating the p53 pathway during oxidative stress (1,2). It functions as a transcriptiol repressor and acts as an oxidative stress mediator by inhibiting thioredoxin activity (2). TXNIP expression is reduced in many types of tumors, and TXNIP overexpression inhibits tumor growth by blocking cell-cycle progression (3). It has recently reported that TXNIP deficiency correlates with a high incidence of hepatocellular carcinoma (HCC) (4). TXNIP and p53 interactions could potentially be a therapeutic target for oxidative stress-related diseases such as hematopoietic maligncies and metabolic diseases (5).
Western Blot: TXNIP Lysate [NBL1-17474] - Western Blot experiments. Left- Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TXNIP
Hum. Adult Placenta; Host: Rabbit . Target Name: TXNIP . Sample Tissue: Human Adult Placenta . Antibody Dilution: 1.0ug/ml.; TXNIP antibody - C-terminal region (ARP52193_P050) in Hum. Adult Placenta cells using Western Blot
Hum. Fetal Lung; Host: Rabbit . Target Name: TXNIP . Sample Tissue: Human Fetal Lung . Antibody Dilution: 1.0ug/ml.; TXNIP antibody - C-terminal region (ARP52193_P050) in Hum. Fetal Lung cells using Western Blot
Human Heart; WB Suggested Anti-TXNIP Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human heart; TXNIP antibody - C-terminal region (ARP52193_P050) in Human Heart cells using Western Blot
Western blot analysis of VDUP-1 expression in Raji cells (Lane 1), K562 cells (Lane 2), KG1 cells (Lane 3), MRC5 cells (Lane 4), IC2Tr cells (Lane 5), HEL cells (Lane 6) and P19 cells (Lane 7) using AM20295AF-N VDUP-1 antibody
Immunoprecipitation of VDUP-1 from Raji cells with AM20295AF-N (Lane 1) or Mouse IgG2b (Lane 2). After immunoprecipitation with the antibody, immunocomplex was resolved on SDS-PAGE and immunoblotted with AM20295AF-N VDUP-1 antibody.
Western blot analysis of Txnip/VDUP1 expression in Raji (1), K562 (Lane 2), KG1 (Lane 3), MRC5 (Lane 4), IC2Tr (Lane 5), HEL (Lane 6), P19 (Lane 7) and WR19L (Lane 8) using AM20296AF-N.
Immunoprecipitation of Txnip/VDUP1 from Raji with AM20296AF-N (Lane 1) or Mouse IgG1 (Lane 2). After immunoprecipitation with the antibody, immunocomplex was resolved on SDS-PAGE and immunoblotted with AM20296AF-N VDUP-1 antibody.
Human Lung; WB Suggested Anti-TXNIP Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Lung; TXNIP antibody - middle region (ARP59054_P050) in Human Lung cells using Western Blot
Western Blot: TXNIP Antibody [NBP1-52909] - This Anti-TXNIP antibody was used in Western Blot of Fetal Heart tissue lysate at a concentration of 1ug/ml.
Immunohistochemistry-Paraffin: TXNIP Antibody [NBP1-84784] Immunohistochemical staining of human cervix, uterine shows strong cytoplasmic positivity in glandular cells.
Western blot analysis of Human Adult Placenta using TXNIP antibody, C-term (GTX45803)
Western blot analysis of Human 293T using TXNIP antibody, C-term (GTX45803)
Detection of TXNIP in Fetal Heart using anti-TXNIP antibody (GTX45803) at 1 µg/mL.
Immunohistochemistry of paraffin-embedded human kidney tissue slide using 18243-1-AP( TXNIP Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human lung tissue slide using 18243-1-AP( TXNIP Antibody) at dilution of 1:50 (under 40x lens)
Immunohistochemistry of paraffin-embedded human kidney tissue slide using 18243-1-AP( TXNIP Antibody) at dilution of 1:50 (under 40x lens)
Immunohistochemistry of paraffin-embedded human lung tissue slide using 18243-1-AP( TXNIP Antibody) at dilution of 1:50 (under 10x lens)
Human stomach tissue were subjected to SDS PAGE followed by western blot with 18243-1-AP(TXNIP antibody) at dilution of 1:300
K-562 cells were subjected to SDS PAGE followed by western blot with 18243-1-AP( TXNIP Antibody) at dilution of 1:600
PC-12 cells were subjected to SDS PAGE followed by western blot with 18243-1-AP( TXNIP Antibody) at dilution of 1:600
Immunofluorescent analysis of HeLa cells using 18243-1-AP( TXNIP Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunofluorescent analysis of HeLa cells using 18243-1-AP( TXNIP Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA337136 | TXNIP / VDUP1 antibody |
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![Western Blot: TXNIP Antibody [TA337136] - Analysis of TxNIP in Raji cell lysate in the 1) absence and 2) presence of immunizing peptide using this antibody. goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/OriGene/NBP2-27095-1-W.jpg) |
Rabbit | Purified | Hu, Prim | WB |
0.1 mg /
€325.00
|
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| OriGene Technologies, Inc. | |||||||
| TA340115 | TXNIP / VDUP1 antibody |
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 |
Rabbit | IgG | Purified | Bov, Can, GP, Hu, Ms, Rb, Rt, Sh | WB |
50 µg /
€325.00
|
|
| OriGene Technologies, Inc. | |||||||
 +2 additional images |
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| TA349090 | TXNIP / VDUP1 antibody |
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 |
Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 mg /
€325.00
|
|
| OriGene Technologies, Inc. | |||||||
| AM20295AF-N | TXNIP / VDUP1 antibody |
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 |
Mouse | IgG2b | JY1 | Azide Free | Hu, Ms | IP, WB |
0.1 mg /
€410.00
|
| Acris Antibodies GmbH | |||||||
| +1 additional image |
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| AM20296AF-N | TXNIP / VDUP1 antibody |
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 |
Mouse | IgG1 | JY2 | Azide Free | Hu, Ms, Rt | IP, P, WB |
0.1 mg /
€420.00
|
| Acris Antibodies GmbH | |||||||
| +1 additional image |
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| ARP52193_P050 | TXNIP / VDUP1 antibody |
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 |
Rabbit | Aff - Purified | African clawed frog, Bov, Can, Hu, Ms, Por, Rt | WB |
50 µg /
€350.00
|
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| AVIVA Systems Biology | |||||||
| +2 additional images |
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| ARP59054_P050 | TXNIP / VDUP1 antibody |
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 |
Rabbit | Aff - Purified | Hu | WB |
50 µg /
€350.00
|
||
| AVIVA Systems Biology | |||||||
| NBP1-52909 | TXNIP / VDUP1 antibody |
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![Western Blot: TXNIP Antibody [NBP1-52909] - This Anti-TXNIP antibody was used in Western Blot of Fetal Heart tissue lysate at a concentration of 1ug/ml.](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/TXNIP Antibody-Western Blot-NBP1-52909-img0001.jpg) |
Rabbit | Aff - Purified | Bov, Can, Hu, Ms, Por, Rt, Sh, Xen | WB |
50 µg /
€440.00
|
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| Novus Biologicals Inc. | |||||||
| NBP1-54578-0.05 | TXNIP / VDUP1 antibody |
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Mouse | IgG1 | JY2 | Purified | Hu, Ms, Rt | C, F, ICC/IF, IP, WB |
50 µg /
€360.00
|
| Novus Biologicals Inc. | |||||||
| NBP1-84784 | TXNIP / VDUP1 antibody |
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![Immunohistochemistry-Paraffin: TXNIP Antibody [NBP1-84784] Immunohistochemical staining of human cervix, uterine shows strong cytoplasmic positivity in glandular cells.](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/TXNIP Antibody-Immunohistochemistry-Paraffin-NBP1-84784-0005.jpg) |
Rabbit | IgG | Aff - Purified | Hu | P |
0.1 ml /
€500.00
|
|
| Novus Biologicals Inc. | |||||||
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP310804 | TXNIP / VDUP1 |
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 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€680.00
|
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| OriGene Technologies, Inc. | |||||
| H00010628-P01 | TXNIP / VDUP1 |
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Human | Purified |
2 µg /
€300.00
|
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| Abnova Taiwan Corp. | |||||
| H00010628-P01-10 | TXNIP / VDUP1 |
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Human |
10 µg /
€380.00
|
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| Abnova Taiwan Corp. | |||||
