TYROBP / DAP12 antibody

Principal name

TYROBP / DAP12 antibody

Alternative names for TYROBP / DAP12 antibody

KARAP, TYRO protein tyrosine kinase-binding protein, DNAX-activation protein 12, Killer-activating receptor-associated protein

SwissProt ID

O43914 (Human), O54885 (Mouse), Q6X9T7 (Rat), Q95J79 (Bovin), Q9TU45 (Pig)

Gene ID

7305 (TYROBP), 22177 (Tyrobp)

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P), Enzyme Immunoassay (E), Flow Cytometry (F)

Background of TYROBP / DAP12 antibody

This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Two alternative transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described, but their full-length nature has not been deterimined. [provided by RefSeq]. Transcript Variant: This variant (2), also known as 112DAP12, uses an alternate in-frame splice site in the coding region, compared to variant 1, resulting in a shorter isoform (2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TYROBP / DAP12 antibody

Western blot analysis of DAP12 expression in rat kidney tissue lysate. Rabbit Purified Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

TYROBP / DAP12 antibody

Predicted cell location: Cytoplasm. Positive control: Human thyroid cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TYROBP antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TYROBP / DAP12 antibody

Western blot analysis of extracts of SK-SEP1 cell line, using TYROBP antibody. Rabbit IgG Purified Hu
0.1 mg / €325.00
  OriGene Technologies, Inc.

TYROBP / DAP12 antibody

Figure 1. Immunoprecipitation using DAP12 antibody on MHC class I (1) and NKp44 (2) positive cells. Rabbit Purified Hu, Ms IP, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

TYROBP / DAP12 (Internal) antibody

Human Uterus (formalin-fixed, paraffin-embedded) stained with TYROBP antibody AP22905PU-N followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Hu, Mky, Ms, Prim, Rb, Sh E, P
50 µg / €470.00
  Acris Antibodies GmbH

TYROBP / DAP12 (C-term) antibody

TYROBP Antibody (C-term) (AP54428PU-N) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TYROBP Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

TYROBP / DAP12 antibody

Western blot analysis of Tyrobp expression in rat kidney tissue lysate. Rabbit Ms, Rt WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

TYROBP / DAP12 antibody

Immunoprecipitation using DAP12 polyclonal antibody on MHC class I ( 1 ) and NKp44 ( 2 ) positive cells. Rabbit IgG Hu, Ms IP
0.1 mg / €400.00
  Abnova Taiwan Corp.

TYROBP / DAP12 antibody

TYROBP / DAP12 Goat Aff - Purified Hu E, P
50 µg / €480.00
  Novus Biologicals Inc.

TYROBP / DAP12 antibody

Immunohistochemistry-Paraffin: DAP12 Antibody [NBP1-85313] Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in hematopoietic cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

TYROBP / DAP12 antibody

TYROBP / DAP12 Rabbit Purified Rt WB
0.2 mg / €290.00
  Torrey Pines Biolabs

TYROBP / DAP12 antibody

TYROBP / DAP12 Rabbit Azide Free Rt WB
0.2 mg / €290.00
  Torrey Pines Biolabs

TYROBP / DAP12 antibody

TYROBP / DAP12 Rabbit Purified Hu WB
0.2 mg / €290.00
  Torrey Pines Biolabs

TYROBP / DAP12 antibody

TYROBP / DAP12 Rabbit Azide Free Hu WB
0.2 mg / €290.00
  Torrey Pines Biolabs

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TYROBP / DAP12 (transcript variant 1)

TYROBP / DAP12 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

TYROBP / DAP12

TYROBP / DAP12 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

TYROBP / DAP12

TYROBP / DAP12 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

TYROBP / DAP12

TYROBP / DAP12 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

TYROBP / DAP12

TYROBP / DAP12 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

TYROBP overexpression lysate

TYROBP overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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