UBASH3B / STS1 antibody

Principal name

UBASH3B / STS1 antibody

Alternative names for UBASH3B / STS1 antibody

KIAA1959, STS-1, Ubiquitin-associated and SH3 domain-containing protein B, Suppressor of T-cell receptor signaling 1, Cbl-interacting protein p70

SwissProt ID

Q8BGG7 (Mouse), Q8TF42 (Human)

Gene ID

84959 (UBASH3B), 72828 (Ubash3b), 2884959 (clpP)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Frozen Sections (C)

Background of UBASH3B / STS1 antibody

Sts-1 is a protein that inhibits endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor. Sts-1 and Sts-2 (formerly p70 and Clip4, respectively) have been found to interact with Cbl, an ubiquitin ligase that plays a critical role in attenuation of receptor tyrosine kinase signaling by inducing ubiquitination and promoting their sorting for endosomal degradation. Sts-1 and Sts-2 contain SH3 domains that interact with Cbl, Ub-associated domains, which bind directly to mono-Ub or to the EGFR/Ub chimera, as well as phosphoglycerate mutase domains that mediate oligomerization of Sts-1/2. Sts-1 and Sts-2 also have been found to negatively regulate signaling pathways that control T cell receptors, which in turn affect the extent and duration of the T cell response to foreign pathogens.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

UBASH3B / STS1 (C-term) antibody

WB using Anti-Sts-1 antibody shows detection of a band ~70 kDa corresponding to mouse Sts-1. Approximately 1.0 ?g of recombinant (truncated) Sts-1-GST was separated by SDS-PAGE and transferred onto nitrocellulose. After blocking the membrane was probed with the primary antibody diluted to 0.3?ug/ml overnight at 4° C followed by washes and reaction with a 1:10,000 dilution of IRDye800 conjugated Gt-a-Rabbit IgG [H&L] MX . Rabbit IgG Aff - Purified Can, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

UBASH3B / STS1 antibody

Host: Rabbit; Target Name: Ubash3b; Sample Tissue: Rat Testis lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

UBASH3B / STS1 antibody

UBASH3B / STS1 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

UBASH3B / STS1 antibody

Western Blot analysis of UBASH3B expression in transfected 293T cell line (H00084959-T01) by UBASH3B MaxPab polyclonal antibody.

Lane 1: UBASH3B transfected lysate(72.70 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

UBASH3B / STS1 antibody

Immunoperoxidase of monoclonal antibody to UBASH3B on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml] Mouse IgG2b 3G7 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

UBASH3B / STS1 antibody

Western blot using Ubash3b polyclonal antibody ( Cat # PAB11329 ) shows detection of a band ~70 kDa correspondingto mouse Ubash3b.
Approximately 1.0 µg of recombinant ( truncated ) Ubash3b-GST was separated by SDS-PAGE and probed with the primary antibody diluted to 0.3 µg/ml. Rabbit Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €560.00
  Abnova Taiwan Corp.

UBASH3B / STS1 antibody

Immunohistochemistry: Sts1 Antibody [NBP1-32592] - analysis of paraffin-embedded SW480 xenograft , using Steryl-sulfatase antibody at 1:100 dilution. Rabbit IgG Hu P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

UBASH3B / STS1 antibody

Immunohistochemistry-Paraffin: Cbl-c Antibody [NBP1-78063] 5 ug/ml to detect signal in a variety of tissues including multi-human, multi-brain and multi-cancer slides. This image shows moderate intracellular positive staining of human pancreatic acinar epithelium at 40X.  The image shows localization of the antibody as the precipitated red signal, with a hematoxylin purple nuclear counterstain. Rabbit Aff - Purified Hu E, P, WB
0.1 mg / €510.00
  Novus Biologicals Inc.

UBASH3B / STS1 antibody

Immunohistochemistry-Paraffin: Sts1 Antibody [NBP1-92456] Immunohistochemical staining of human kidney shows strong cytoplasmic positivity, with a granular pattern in cells in tubules. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

UBASH3B / STS1

UBASH3B / STS1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

UBASH3B / STS1

UBASH3B / STS1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

UBASH3B / STS1

UBASH3B / STS1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

UBASH3B / STS1

UBASH3B / STS1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

UBASH3B / STS1

UBASH3B / STS1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

STS-1 293T Cell Transient Overexpression Lysate(Denatured)

STS-1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

UBASH3B overexpression lysate

UBASH3B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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