UBE2D1 / SFT antibody

Principal name

UBE2D1 / SFT antibody

Alternative names for UBE2D1 / SFT antibody

Ubiquitin-conjugating enzyme E2 D1, Ubiquitin-protein ligase D1, Ubiquitin carrier protein D1, UBC4/5 homolog, E2(17)KB 1, UBCH5, UBCH5A

SwissProt ID

P51668 (Human)

Gene ID

7321 (UBE2D1)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Por (Porcine), Rt (Rat), Ze (Zebrafish), African clawed frog

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of UBE2D1 / SFT antibody

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitition involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitition of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].

General readings

Windheim M., et al. (2008) Biochem. J. 409:723-729.
Pabarcus M.K., et al. (2009) Arch. Biochem. Biophys 483:66-74.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

UBE2D1 / SFT antibody

  Rabbit anti-UBE2D1 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using UBE2D1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

UBE2D1 / SFT antibody

  UBE2D1 mouse monoclonal antibody, clone OTI1E7 (formerly 1E7)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY UBE2D1 (RC205621, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-UBE2D1. Mouse IgG1 OTI1E7 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

UBE2D1 / SFT (1-95) antibody

Formalin-Fixed, Paraffin-Embedded Human Breast, Epithelium stained with UBE2D1 Antibody Cat.-No AM32884PU-N Mouse IgG2a 2C6 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

UBE2D1 / SFT (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

UBE2D1 - human gene knockout kit via CRISPR

UBE2D1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

UBE2D1 - human gene knockout kit via CRISPR

UBE2D1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

UBE2D1 - human gene knockout kit via CRISPR

UBE2D1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

UBE2D1 - human gene knockout kit via CRISPR

UBE2D1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

UBE2D1 / SFT

  Recombinant protein of human ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) (UBE2D1)  
UBE2D1 / SFT Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

UBE2D1 / SFT (1-147, His-tag)

UBE2D1 / SFT Human Purified > 95 % E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

UBE2D1 / SFT (1-147, His-tag)

UBE2D1 / SFT Human Purified > 95 % E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, UBE2D1 (mGFP-tagged) - Human ubiquitin-conjugating enzyme E2D 1 (UBE2D1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, UBE2D1 (mGFP-tagged) - Human ubiquitin-conjugating enzyme E2D 1 (UBE2D1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, UBE2D1 (Myc-DDK tagged) - Human ubiquitin-conjugating enzyme E2D 1 (UBE2D1), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, UBE2D1 (Myc-DDK tagged) - Human ubiquitin-conjugating enzyme E2D 1 (UBE2D1), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

13 Item(s)

per page
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