UBE2O antibody

Principal name

UBE2O antibody

Alternative names for UBE2O antibody

Ubiquitin-conjugating enzyme E2 O, Ubiquitin-protein ligase O, Ubiquitin carrier protein O, E2-230K, KIAA1734, Ubiquitin-conjugating enzyme E2 of 230 kDa

SwissProt ID

Q6ZPJ3 (Mouse), Q9C0C9 (Human)

Gene ID

63893 (UBE2O)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Goat, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of UBE2O antibody

UBE20, also known as E2-230K, is a 1,292 amino acid member of the uniquitin-conjugating enzyme family that is involved in protein modification. Expressed predominately in heart and skeletal muscle, UBE2O functions to catalyze the ATP-dependent covalent attachment of ubiquitin to select proteins, thereby targeting the ubiquitinated proteins for proteasomal degradation. The gene encoding UBE2O maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

General readings

Yokota T et al. Identification, tissue expression, and chromosomal position of a novel gene encoding human ubiquitin-conjugating enzyme E2-230k. Gene 267:95-100 (2001). PubMed PMID: 11311559

15 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

UBE2O antibody

WB Suggested Anti-UBE2O Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: RPMI 8226 cell lysateUBE2O is supported by BioGPS gene expression data to be expressed in RPMI 8226 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

UBE2O (C-term) antibody

Formalin-Fixed, Paraffin-Embedded Human Heart stained with UBE2O antibody Cat.-No AP31922PU-N at 4 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, P
0.1 mg / €340.00
  Acris Antibodies GmbH

UBE2O antibody

Western Blot analysis of UBE2O expression in transfected 293T cell line (H00063893-T02) by UBE2O MaxPab polyclonal antibody.

Lane 1: UBE2O transfected lysate(81.70 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

UBE2O antibody

UBE2O Mouse IgG2a 2C10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

UBE2O antibody

UBE2O Goat Hu E
0.1 mg / €400.00
  Abnova Taiwan Corp.

UBE2O antibody

UBE2O Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

UBE2O antibody

UBE2O Goat IgG Aff - Purified Hu E, P
0.1 mg / €320.00
  Novus Biologicals Inc.

UBE2O antibody

Western Blot and  Immunoprecipitation: UBE2O Antibody [NBP1-03336] - Detection of Human UBE2O bon HeLa whole cell lysate using NBP1-03336. Rabbit IgG Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

UBE2O antibody

Western Blot:   UBE2O Antibody [NBP1-32020]- (30 ug of whole cell lysate) A: Hep G2  5% SDS PAGE  diluted at 1:500 Rabbit IgG Hu ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

UBE2O

UBE2O Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

UBE2O

UBE2O Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

UBE2O

UBE2O Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

UBE2O

UBE2O Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

UBE2O

UBE2O Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

UBE2O overexpression lysate

UBE2O overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

15 Item(s)

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