UBE2V2 antibody

Principal name

UBE2V2 antibody

Alternative names for UBE2V2 antibody

Ubiquitin-conjugating enzyme E2 variant 2, UEV2, MMS2, EDAF-1, EDPF-1, Enterocyte differentiation-associated factor EDAF-1, Enterocyte differentiation-promoting factor, Vitamin D3-inducible protein, DDVit 1

SwissProt ID

Q15819 (Human), Q5F3Z3 (Chick), Q6PEH5 (Danre), Q7M767 (Rat), Q7ZYP0 (Xenla), Q9D2M8 (Mouse)

Gene ID

7336 (UBE2V2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine)

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of UBE2V2 antibody

The differentiation and activation of monocytes (MO) and monocytic cells is modulated by 1alpha,25-dihydroxyvitamin D3 (Vitamin D3). Recently, using mRNA Differential Display technology, Fritsche J, et al have identified a gene which is induced in freshly isolated human blood MO that are cultured for 4 hours with Vitamin D3 (1). This cDNA encodes a putative 16.5 kD protein. The product of this gene has structural homology with yeast MMS2p and human CROC-1), which defines a structurally and functionally conserved Ubc-like protein family (2). This protein was called Ubiquitin E2 variant (UBE2V2) or MMS2 (methyl methanesulfonate sensitive 2). The yeast UEV protein, Mms2, is required together with Ubc13 for RAD6/RAD18-dependent postreplicative DNA repair in yeast (3). These proteins also play a central role in the assembly of K63-linked polyubiquitin chains (4,5) UEV/Ubc complexes have been implicated in the assembly of Lys63-linked polyubiquitin chains that act as a novel signal in postreplicative DNA repair and IkBa kinase activation. Recent crystal structure analysis provides direct evidence that the Mms2/Ubc13 heterodimer is necessary for DNA repair (6,7).

General readings

Fritsche J, Rehli M, Krause SW, Andreesen R, Kreutz M.
Molecular cloning of a 1alpha,25-dihydroxyvitamin D3-inducible transcript (DDVit 1) in human blood monocytes.
Biochem Biophys Res Commun. 1997 Jun 18;235(2):407-12.
PMID: 9199207

13 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

UBE2V2 (N-term) antibody

TA302785 staining (0.5µg/ml) of human brain lysate (RIPA buffer, 30µg total protein per lane).  Primary incubated for 12 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

UBE2V2 antibody

UBE2V2 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

UBE2V2 antibody

Detection of UBE2V2 in HL-60 cell lysate with UBE2V2 polyclonal antibody ( Cat # PAB0193 ) at 2µg/ml dilution. Rabbit Hu WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

UBE2V2 antibody

UBE2V2 polyclonal antibody ( Cat # PAB6156 ) staining ( 0.5 µg/ml ) of human brain lysate ( RIPA buffer, 30 µg total protein per lane ) . Primary incubated for 12 hour. Detected by western blot using chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

UBE2V2 antibody

EB 100-1026 staining (0.5µg/ml) of Human Brain lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

UBE2V2 antibody

Detection of UBE2V2 in HL-60 cell lysate with anti-UBE2V2 pcAb (Cat. NB100-56360) at 2ug/ml dilution. Rabbit IgG Aff - Purified Hu WB
0.1 mg / €320.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

UBE2V2 (1-145, His-tag)

UBE2V2 Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

UBE2V2 (1-145, His-tag)

UBE2V2 Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

UBE2V2

UBE2V2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

UBE2V2

UBE2V2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

UBE2V2

UBE2V2 Human Purified
0.1 mg / €380.00
  Novus Biologicals Inc.

UBE2V2

UBE2V2 Human Purified
0.5 mg / €870.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

UBE2V2 293T Cell Transient Overexpression Lysate(Denatured)

UBE2V2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

13 Item(s)

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