UBE4B antibody

Principal name

UBE4B antibody

Alternative names for UBE4B antibody

Ubiquitin conjugation factor E4 B, UFD2, HDNB1, KIAA0684, Ubiquitin fusion degradation protein 2, Homozygously deleted in neuroblastoma 1

SwissProt ID

O95155 (Human), Q9ES00 (Mouse)

Gene ID

10277 (UBE4B)

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of UBE4B antibody

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B is an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. The gene that encodes the protein is also the strongest candidate in the neuroblastoma tumor suppressor genes. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human UBE4B with an internal ID of P31336

General readings

Olsen,J.V., (2006) Cell 127 (3), 635-648

9 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

UBE4B antibody

  Rabbit polyclonal antibody to UBE4B (ubiquitination factor E4B (UFD2 homolog, yeast))  
Sample (30 ug of whole cell lysate). A: Hep G2 . 5% SDS PAGE. TA308624 diluted at 1:10000 Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

UBE4B antibody

  Rabbit Polyclonal Anti-UBE4B Antibody  
WB Suggested Anti-UBE4B Antibody Titration: 0.2-1 ug/ml; Positive Control: Human brain Rabbit IgG Purified Can, Hu, Por WB
50 µg / €325.00
  OriGene Technologies, Inc.

UBE4B (N-term) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

UBE4B - human gene knockout kit via CRISPR

UBE4B - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

UBE4B - human gene knockout kit via CRISPR

UBE4B - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

UBE4B - human gene knockout kit via CRISPR

UBE4B - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

UBE4B - human gene knockout kit via CRISPR

UBE4B - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, UBE4B (mGFP-tagged)-Human ubiquitination factor E4B (UBE4B), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, UBE4B (mGFP-tagged)-Human ubiquitination factor E4B (UBE4B), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

Lenti ORF particles, UBE4B (Myc-DDK-tagged)-Human ubiquitination factor E4B (UBE4B), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, UBE4B (Myc-DDK-tagged)-Human ubiquitination factor E4B (UBE4B), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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