UBR1 antibody

Principal name

UBR1 antibody

Alternative names for UBR1 antibody

N-recognin-1, E3 ubiquitin-protein ligase UBR1, Ubiquitin-protein ligase E3-alpha-1, Ubiquitin-protein ligase E3-alpha-I

SwissProt ID

O70481 (Mouse), Q8IWV7 (Human)

Gene ID

197131 (UBR1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ye (Yeast)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of UBR1 antibody

UBR1 is an E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-termil residues that are destabilizing according to the N-end rule, leading to their ubiquitition and subsequent degradation. UBR1 may be involved in pancreatic homeostasis.The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-termil residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

UBR1 antibody

  Rabbit Polyclonal Anti-UBR1 Antibody  
WB Suggested Anti-UBR1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ye WB
50 µg / €325.00
  OriGene Technologies, Inc.

UBR1 antibody

Western blot analysis of extracts from HepG2/Jurkat cells, using UBR1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €230.00
  Assay Biotech

UBR1 antibody

Western blot analysis of extracts from HepG2/Jurkat cells, using UBR1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

UBR1 - human gene knockout kit via CRISPR

UBR1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

UBR1 - human gene knockout kit via CRISPR

UBR1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

UBR1 - human gene knockout kit via CRISPR

UBR1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

UBR1 - human gene knockout kit via CRISPR

UBR1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

UBR1 overexpression lysate

UBR1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, UBR1 (Myc-DDK tagged) - Human ubiquitin protein ligase E3 component n-recognin 1 (UBR1), 200 uL, >10^7 TU/mL

Lenti ORF particles, UBR1 (Myc-DDK tagged) - Human ubiquitin protein ligase E3 component n-recognin 1 (UBR1), 200 uL, >10^7 TU/mL  
200 µl / €2,280.00
  OriGene Technologies, Inc.

9 Item(s)

per page
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