UGDH antibody

Principal name

UGDH antibody

Alternative names for UGDH antibody

UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH

SwissProt ID

O60701 (Human), O70199 (Rat), O70475 (Mouse), P12378 (Bovin)

Gene ID

7358 (UGDH), 281564, 22235 (Ugdh), 83472

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig), Gt (Goat), Rb (Rabbit), Ye (Yeast), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Dot blot (Dot), Immunodiffusion (ID), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Radioimmunoassay (R), Paraffin Sections (P)

Background of UGDH antibody

UDP-GlcDH (also called UDP-glucose 6-dehydrogese, UGDH or UDPGDH) is a member of the UDP-glucose/GDP-mannose dehydrogese family. UDP-GlcDH converts UDP-glucose to UDP-glucuronic acid, which is a crucial component in the biosynthesis of the glycosaminoglycans, hyaluron, heparan sulfate and chondroitin sulfate. Found as common components of the extracellular matrix, these glycosaminoglycans are significant in sigl transduction, cell migration, cancer growth and cancer metastasis. UDP-glucuronic acid (UDP-GlcA) is needed in the liver for the excretion of toxic compounds. UDP-GlcDH is a ubiquitously expressed protein most abundant in the liver. The protein structure of UDP-GlcDH was first alyzed in cow liver and found to be a homohexamer. This structure is well conserved between species and phyla with an overall 97% sequence identity shared between different species of mammals. Research indicates that UDP-GlcDH expression is upregulated by TGF? and downregulated by hypoxia.

General readings

Bontemps Y., et al. (2003) J Biol Chem. 278(24):21566-75.
Vatsyayan J., et al. (2006) Biosci Biotechnol Biochem. 70(2):401-10.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

UGDH antibody

  Rabbit anti-UGDH Polyclonal Antibody  
Western blot analysis of HepG2 cell and HeLa cell lysate using UGDH antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

UGDH antibody

  Rabbit polyclonal anti-UGDH antibody  
Western blot analysis of extracts from COLO cells, using UGDH antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

UGDH antibody

  Rabbit Polyclonal Anti-UGDH Antibody  
Host: Rabbit; Target Name: Ugdh; Sample Tissue: Rat Stomach lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Rb, Rt, Ye, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

UGDH antibody

UGDH Rabbit IgG Azide Free Bov Dot, E, ICC/IF, ID, IP, R, WB
10 mg / €240.00
  Acris Antibodies GmbH

UGDH antibody

UGDH Rabbit IgG Biotin Bov Dot, E, ICC/IF, ID, IP, R, WB
1 ml / €350.00
  Acris Antibodies GmbH

UGDH antibody

UGDH Rabbit IgG Aff - Purified Bov Dot, E, ICC/IF, ID, IP, R, WB
1 mg / €440.00
  Acris Antibodies GmbH

UGDH (C-term) antibody

UGDH Antibody (C-term) (AP54453PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of UGDH Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

UGDH antibody

Western blot analysis of extracts from COLO cells, using UGDH Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

UGDH antibody

Western blot analysis of extracts from COLO cells, using UGDH Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

UGDH - human gene knockout kit via CRISPR

UGDH - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

UGDH - human gene knockout kit via CRISPR

UGDH - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

UGDH - human gene knockout kit via CRISPR

UGDH - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

UGDH - human gene knockout kit via CRISPR

UGDH - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ugdh - mouse gene knockout kit via CRISPR

Ugdh - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Ugdh - mouse gene knockout kit via CRISPR

Ugdh - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ugdh - mouse gene knockout kit via CRISPR

Ugdh - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ugdh - mouse gene knockout kit via CRISPR

Ugdh - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

UGDH

  Recombinant protein of human UDP-glucose dehydrogenase (UGDH)  
UGDH Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

UGDH (1-494, His-tag)

Recombinant human UGDH, 1-494 aa, His-tagged Human Purified > 95 % by SDS – PAGE E. coli
0.25 mg / €750.00
  Acris Antibodies GmbH

UGDH (1-494, His-tag)

Recombinant human UGDH, 1-494 aa, His-tagged Human Purified > 95 % by SDS – PAGE E. coli
50 µg / €300.00
  Acris Antibodies GmbH

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