UIMC1 / RAP80 antibody

Principal name

UIMC1 / RAP80 antibody

Alternative names for UIMC1 / RAP80 antibody

Receptor-associated protein 80, RXRIP110, BRCA1-A complex subunit RAP80, Ubiquitin interaction motif-containing protein 1, Retinoid X receptor-interacting protein 110

SwissProt ID

A0P8Z5 (Pig), Q5U5Q9 (Mouse), Q96RL1 (Human)

Gene ID

51720 (UIMC1)

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Por (Porcine), Rt (Rat)

Available hosts

Rabbit, Mouse, Goat

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of UIMC1 / RAP80 antibody

RAP80 was initially identified as zinc-finger containing nuclear protein that is highly expressed in testis and interacts with the retinoid-related testis-associated receptor (RTR). Later experiments revealed that RAP80 is recruited by the Coiled-coil domain 98 (CCDC98) protein to the breast cancer-1 protein BRCA1, allowing the formation of BRCA1 foci in response to DNA damage caused by ionizing radiation. Both RAP80 and CCDC98 are required for DNA damage resistance, G2-M checkpoint control, and DNA repair. Cells depleted of either RAP80 or CCDC98 exhibited increased sensitivity to ionizing radiation, although not as much as in BRCA1-depleted cells, suggesting that RAP80 and CCDC98 control only part of the DNA damage response role of BRCA1. At least four isoforms of RAP80 are known to exist.

19 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

UIMC1 / RAP80 (C-term) antibody

Western blot analysis of RAP80 in 293 cell lysate in (A) the absence and (B) presence of blocking peptide with RAP80 antibody at 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

UIMC1 / RAP80 (N-term) antibody

Immunohistochemistry of RAP80 in human spleen tissue with RAP80 antibody at 2.5 ug/ml. Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

UIMC1 / RAP80 antibody

Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

UIMC1 / RAP80 antibody

Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

UIMC1 / RAP80 Control Peptide

UIMC1 / RAP80
50 µg / €160.00
  Acris Antibodies GmbH

UIMC1 / RAP80 Control Peptide

UIMC1 / RAP80
50 µg / €160.00
  Acris Antibodies GmbH

UIMC1 / RAP80 antibody

Western Blot analysis of UIMC1 expression in transfected 293T cell line (H00051720-T01) by UIMC1 MaxPab polyclonal antibody.

Lane 1: RAP80 transfected lysate(42.35 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

UIMC1 / RAP80 antibody

Immunoprecipitation of UIMC1 transfected lysate using anti-UIMC1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with UIMC1 MaxPab mouse polyclonal antibody (B01) (H00051720-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

UIMC1 / RAP80 antibody

Western Blot analysis of UIMC1 expression in transfected 293T cell line (H00051720-T01) by UIMC1 MaxPab polyclonal antibody.

Lane 1: UIMC1 transfected lysate(43.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

UIMC1 / RAP80 antibody

Immunohistochemistry of UIMC1 in human spleen tissue with UIMC1 polyclonal antibody ( Cat # PAB13295 ) at 2.5 µg/ml. Rabbit Hu, Ms P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

UIMC1 / RAP80 antibody

Immunohistochemistry of UIMC1 in human spleen tissue with UIMC1 polyclonal antibody ( Cat # PAB13296 ) at 2.5 µg/ml. Rabbit Hu, Ms P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

UIMC1 / RAP80 antibody

Western Blot and Immunoprecipitation: RAP80 Antibody [NB100-2347] - Detection of Human RAP80 on HeLa whole cell lysate using NB100-2347. RAP80 was also immunoprecipitated using rabbit  anti-RAP80 antibody NB100-2346. Rabbit Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

UIMC1 / RAP80 antibody

Immunohistochemistry-Paraffin: RAP80 Antibody [NBP1-76828] - Human spleen tissue with RAP80 antibody at 2.5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

UIMC1 / RAP80 antibody

Immunohistochemistry-Paraffin: RAP80 Antibody [NBP1-76829] - Human spleen tissue with RAP80 antibody at 2.5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

UIMC1 / RAP80 antibody

Immunohistochemistry-Paraffin: RAP80 Antibody [NBP1-87156] - Immunohistochemical staining of human testis shows moderate nuclear positivity in cells in seminiferus ducts. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

UIMC1 / RAP80

UIMC1 / RAP80 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

UIMC1 / RAP80

UIMC1 / RAP80 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Antibody Pairs

Catalog No.    

UIMC1 (Human) IP-WB Antibody Pair

UIMC1 (Human) IP-WB Antibody Pair  
1 set / €710.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

RAP80 293T Cell Transient Overexpression Lysate(Denatured)

RAP80 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

19 Item(s)

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