ULBP2 / NKG2D ligand 2 antibody

Principal name

ULBP2 / NKG2D ligand 2 antibody

Alternative names for ULBP2 / NKG2D ligand 2 antibody

UL16-binding protein 2, NKG2DL2, N2DL2, N2DL-2, ALCAN-alpha, RAET1H, UNQ463/PRO791, Retinoic acid early transcript 1H

SwissProt ID

Q9BZM5 (Human)

Gene ID

80328 (ULBP2)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Flow Cytometry (F), Enzyme Immunoassay (E), Paraffin Sections (P), Neutralisation (NEUT)

Background of ULBP2 / NKG2D ligand 2 antibody

ULBP2, also known as NKG2D ligand 2, belongs to the MHC class I family. This protein is ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.

General readings

Cosman D., et al. (2001) Immunity. 14:123-133Dunn C., et al. (2003) J. Exp. Med. 197:1427-1439

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  2. Highly Validated (1)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ULBP2 / NKG2D ligand 2 antibody

Immunohistochemical staining of human stomach shows cytoplasmic positivity in a subset of inflammatory cells.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only. Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ULBP2 / NKG2D ligand 2 antibody

Western Blot analysis of ULBP2 expression in transfected 293T cell line (H00080328-T01) by ULBP2 MaxPab polyclonal antibody.

Lane 1: ULBP2 transfected lysate(27.17 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), F, WB
50 µg / €370.00
  Abnova Taiwan Corp.

ULBP2 / NKG2D ligand 2 antibody

Western Blot: ULBP2 Antibody [27080002] - Samples:  Lane 1, Marker [kDa]: 250, 130, 95, 72, 55, 36, 28, 17, 11  Lane 2, RT-4  Lane 3, U-251MG sp  Lane 4, Human Plasma  Lane 5, Liver  Lane 6, Tonsil ,   Target weight [kDa]:   27   Validation score:   2   Validation description:  Supportive - Band of predicted size in kDa (+/-20%) with additional bands present. Rabbit Hu E, P, WB
50 µg / €390.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ULBP2 / NKG2D ligand 2

ULBP2 / NKG2D ligand 2 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €299.00
  OriGene Technologies, Inc.

ULBP2 / NKG2D ligand 2

ULBP2 / NKG2D ligand 2 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

ULBP2 / NKG2D ligand 2 (26-216, His-tag)

ULBP2 / NKG2D ligand 2 Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

ULBP2 / NKG2D ligand 2 (26-216, His-tag)

ULBP2 / NKG2D ligand 2 Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

ULBP2 / NKG2D ligand 2

ULBP2 / NKG2D ligand 2 Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ULBP2 293T Cell Transient Overexpression Lysate(Denatured)

ULBP2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

ULBP2 overexpression lysate

ULBP2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

10 Item(s)

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