UNC13D antibody

Principal name

UNC13D antibody

Alternative names for UNC13D antibody

Protein unc-13 homolog D, Munc13-4

SwissProt ID

Q70J99 (Human), Q9R189 (Rat)

Gene ID

201294 (UNC13D), 6201294 (IPR000688)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Dot blot (Dot), Flow Cytometry (F), Frozen Sections (C)

Background of UNC13D antibody

This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. This product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognise native protein in any application.

General readings

1. Feldmann J, Callebaut I, Raposo G, Certain S, Bacq D, Dumont C, Lambert N, Ouachee-Chardin M, Chedeville G, Tamary H, Minard-Colin V, Vilmer E, Blanche S,
Le Deist F, Fischer A, de Saint Basile G.
Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Cell. 2003 Nov 14;115(4):461-73.
PMID: 14622600

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

UNC13D antibody

AP16521PU-N (2.5µg/ml) staining of paraffin embedded Human Thymus. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat Aff - Purified Can, Hu, Ms, Rt P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

UNC13D (C-term) antibody

TA305698 (2ug/ml) staining of Human T-lymphocyte lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

UNC13D antibody

Sample (30 ug of whole cell lysate). A: Jurkat. B: K562. 5% SDS PAGE. TA308332 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

UNC13D antibody

Host: Rabbit; Target Name: UNC13D; Sample Tissue: Fetal Lung lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

UNC13D antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY UNC13D (RC209141, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-UNC13D. Mouse IgG1 OTI1F4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

UNC13D antibody

UNC13D MaxPab polyclonal antibody. Western Blot analysis of UNC13D expression in human spleen. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

UNC13D antibody

UNC13D Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

UNC13D antibody

Western Blot analysis of UNC13D expression in transfected 293T cell line (H00201294-T02) by UNC13D MaxPab polyclonal antibody.

Lane 1: UNC13D transfected lysate(123.30 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

UNC13D antibody

UNC13D monoclonal antibody (M05), clone 2C7. Western Blot analysis of UNC13D expression in NIH/3T3(Cat # L018V1 ). Mouse IgG2a 2C7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

UNC13D antibody

Detection limit for recombinant GST tagged UNC13D is approximately 1ng/ml as a capture antibody. Mouse IgG2a 1E11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

UNC13D antibody

UNC13D polyclonal antibody ( Cat # PAB6640 ) ( 2 µg/ml ) staining of human T-lymphocyte lysate ( 35 µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

UNC13D antibody

UNC13D polyclonal antibody ( Cat # PAB7073 ) ( 2.5 µg/ml ) staining of paraffin embedded human thymus. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat Hu, Ms E, P, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

UNC13D antibody

Western Blot: [NB100-1434]-2ug/ml  staining of Human T-lymphocyte lysate (35ug protein in RIPA buffer). Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

UNC13D antibody

NB100-41385 (2.5ug/ml) staining of paraffin embedded Human Thymus. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

UNC13D antibody

Western Blot: Munc 13-4 Antibody [NBP1-31072] - Western blot analysis of Munc 13-4 Antibody on: A:MOLT4 7.5% SDS PAGE diluted at 1:500 Rabbit IgG Hu Dot, ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

UNC13D antibody

Western Blot: Munc 13-4 Antibody (EPR4914) [NBP1-95723] - 4, and (E) RAW264.7 cell lysates using anti-Munc 13-4. Rabbit EPR4914 Purified Hu, Ms F, ICC/IF, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

UNC13D

UNC13D Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

UNC13D

UNC13D Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

UNC13D

UNC13D Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

UNC13D 293T Cell Transient Overexpression Lysate(Denatured)

UNC13D 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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