UNC13D antibody

Principal name

UNC13D antibody

Alternative names for UNC13D antibody

Protein unc-13 homolog D, Munc13-4

SwissProt ID

Q70J99 (Human), Q9R189 (Rat)

Gene ID

201294 (UNC13D), 192177 (Unc13d)

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Rt (Rat), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Goat, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of UNC13D antibody

This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-termil phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq, Jul 2008].

General readings

1. Feldmann J, Callebaut I, Raposo G, Certain S, Bacq D, Dumont C, Lambert N, Ouachee-Chardin M, Chedeville G, Tamary H, Minard-Colin V, Vilmer E, Blanche S,
Le Deist F, Fischer A, de Saint Basile G.
Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Cell. 2003 Nov 14;115(4):461-73.
PMID: 14622600

1 Item(s)

per page

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

UNC13D

  Recombinant protein of human unc-13 homolog D (C. elegans) (UNC13D)  
UNC13D Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €788.00
  OriGene Technologies, Inc.

1 Item(s)

per page
  • LinkedIn