uPA / PLAU antibody

Principal name

uPA / PLAU antibody

Alternative names for uPA / PLAU antibody

Urokinase-type plasminogen activator, U-plasminogen activator, Urokinase, Urokinase-type plasminogen activator long chain A, Urokinase-type plasminogen activator short chain A, Urokinase-type plasminogen activator chain B

SwissProt ID

P00749 (Human), P04185 (Pig), P06869 (Mouse), P15120 (Chick), P29598 (Rat), Q05589 (Bovin), Q6SLL2 (Canfa), Q8MHY7 (Rabit)

Gene ID

5328 (PLAU), 18792 (Plau), 100008633, 403426

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Rt (Rat), Rb (Rabbit)

Available hosts

Mouse, Goat, Rabbit, Sheep

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Functional assay (FN), Frozen Sections (C), Paraffin Sections (P), Immunoprecipitation (IP), Radioimmunoassay (R), Immunocytochemistry/Immunofluorescence (ICC/IF), Dot blot (Dot)

Background of uPA / PLAU antibody

uPA (urokinase-type plasminogen activator) and tPA (tissue plasminogen activator) are serine proteases that are members of the trypsin family, and they are essential to the intrinsic coagulation system. tPA is primarily involved in fibrinolysis, whereas uPA principally mediates cell migration and tissue remodeling processes. uPA and tPA are responsible for cleaving plasminogen, a large serum beta-globulin that is deposited on the Fibrin strands within a thrombus. uPA and tPA preferentially target plasminogen at the Arg-Val bond to produce plasmin (also designated fibrinolysin), which is a trypsin-like enzyme that acts on Arg-Lys bonds in Fibrin and Fibrinogen and contributes to the systematic activation of the coagulation cascade. uPA and tPA each consist of two chains that are designated A and B. The A chain of uPA can be cleaved, resulting in low and high molecular mass forms. uPA and tPA are regulated by the serpin family members PAI-1 and PAI-2, which are serine proteinase inhibitors that complex with uPA, tPA and other targeted proteinases and then slowly disassociate to produce cleaved species that fold into stable inactive conformations.

General readings

Morgan H, Hill PA. Human breast cancer cell-mediated bone collagen degradation requires plasminogen activation and matrix metalloproteinase activity. Cancer Cell Int. 2005 Feb 08;5(1):1. PMID: 15701164

  1. Quick-Filters:
  2. Cited (2)
  3. Highly Validated (1)

Items 1 to 20 of 54 total

per page
Page:
  1. 1
  2. 2
  3. 3

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

uPA / PLAU antibody

uPA / PLAU Goat Serum Hu C, E, P
0.1 ml / €220.00
  Acris Antibodies GmbH

uPA / PLAU antibody

uPA / PLAU Goat Serum Hu C, E, P
20 µl / €120.00
  Acris Antibodies GmbH

uPA / PLAU antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PLAU mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805243) Mouse IgG2a OTI5H4 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

uPA / PLAU (C-term) antibody

TA302671 (0.3µg/ml) staining of 293 lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
20 µg / €200.00
  Acris Antibodies GmbH

uPA / PLAU (C-term) antibody

TA302671 (0.3µg/ml) staining of 293 lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

uPA / PLAU antibody

Predicted cell location: Cytoplasm. Positive control: Human colon and liver cancer tissue . Recommended dilution: 1/10-50  The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using PLAU antibody at dilution 1/10, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

uPA / PLAU antibody

Predicted cell location: Cytoplasm. Positive control: Human brain and gastric cancer tissue . Recommended dilution: 1/10-50  The image on the left is immunohistochemistry of paraffin-embedded human brain tissue using PLAU antibody at dilution 1/10, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

uPA / PLAU antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PLAU (RC202083, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PLAU. Mouse IgG1 OTI1D4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

uPA / PLAU antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PLAU (RC202083, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PLAU. Mouse IgG1 OTI6H4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

uPA / PLAU antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PLAU (RC202083, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PLAU. Mouse IgG2a OTI6H1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

uPA / PLAU antibody

MAb to Mouse Urokinase (3µg/ml) - Secondary: Goat anti Mouse IgG, Alk. Phos. (1:3,000) - Lane 1: 0.5µg Mouse Urokinase (non-reduced) - Lane 2: 0.5µg MuPA + 2.5ug CPAI (non-reduced) - Lane 3: Molecular weight standards Mouse IgG1 B042M Purified Ms WB
1 mg / €1,290.00
  Acris Antibodies GmbH

uPA / PLAU antibody

MAb to Mouse uPA (3µg/ml) - Secondary:  Goat anti Mouse IgG Alk. Phos. (1:3,000) - Lane 1: 0.5µg Mouse Urokinase (non-reduced) - Lane 2: 0.5µg Mouse uPA + 2.5ug CPAI (non-reduced) Mouse IgG1 B043M Purified Ms WB
1 mg / €1,290.00
  Acris Antibodies GmbH

uPA / PLAU antibody

uPA / PLAU Mouse IgG1 PGM2005 Purified Hu C, Dot, E, R, WB
1 ml / €370.00
  Acris Antibodies GmbH

uPA / PLAU antibody

uPA / PLAU Rabbit Purified Hu E, WB
1 mg / €690.00
  Acris Antibodies GmbH

uPA / PLAU antibody

uPA / PLAU Rabbit Purified Ms E, WB
0.2 mg / €320.00
  Acris Antibodies GmbH

uPA / PLAU (N-term) antibody

Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with PLAU antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €380.00
  Acris Antibodies GmbH

uPA / PLAU (C-term) antibody

Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with PLAU antibody (C-term ), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

uPA / PLAU antibody

Immunohistochemistry (IHC) analyzes of uPA antibody (Cat.-No.: AP20580PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu P
0.1 mg / €350.00
  Acris Antibodies GmbH

uPA / PLAU antibody

uPA / PLAU Goat IgG Aff - Purified Hu C, Dot, E, P, WB
0.5 mg / €340.00
  Acris Antibodies GmbH

uPA / PLAU antibody

uPA / PLAU Rabbit IgG Aff - Purified Hu C, Dot, E, P, WB
0.5 mg / €340.00
  Acris Antibodies GmbH

Items 1 to 20 of 54 total

per page
Page:
  1. 1
  2. 2
  3. 3
  • LinkedIn