UPB1 / BUP1 antibody

Principal name

UPB1 / BUP1 antibody

Alternative names for UPB1 / BUP1 antibody

BUP-1, Beta-ureidopropionase, Beta-alanine synthase, N-carbamoyl-beta-alanine amidohydrolase

SwissProt ID

Q03248 (Rat), Q8VC97 (Mouse), Q9UBR1 (Human)

Gene ID

51733 (UPB1), 103149 (Upb1)

Available reactivities

Hu (Human), Arabidopsis, Ce (C. elegans), Can (Canine), Chk (Chicken), Dros (Drosophila), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Gt (Goat), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of UPB1 / BUP1 antibody

UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activityThis gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.

General readings

van (2004) Hum. Mol. Genet. 13 (22), 2793-2801

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

UPB1 / BUP1 antibody

  Rabbit Polyclonal Anti-UPB1 Antibody  
WB Suggested Anti-UPB1 Antibody Titration: 2.5 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

UPB1 / BUP1 antibody

  Rabbit Polyclonal Anti-UPB1 Antibody  
WB Suggested Anti-UPB1 Antibody Titration: 0.2-1 ug/ml; Positive Control: PANC1 cell lysate; UPB1 is supported by BioGPS gene expression data to be expressed in PANC1 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

Upb1 - mouse gene knockout kit via CRISPR

Upb1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

UPB1 / BUP1

  Recombinant protein of human ureidopropionase, beta (UPB1)  
UPB1 / BUP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

UPB1 / BUP1

  Recombinant protein of human ureidopropionase, beta (UPB1)  
UPB1 / BUP1 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €399.00
  OriGene Technologies, Inc.

UPB1 / BUP1 (full length, N-term HIS tag)

  Purified recombinant protein of Human ureidopropionase, beta (UPB1), full length, with N-terminal HIS tag, expressed in E. coli, 50ug  
UPB1 / BUP1 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Upb1 (GFP-tagged) - Mouse ureidopropionase, beta (Upb1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Upb1 (GFP-tagged) - Mouse ureidopropionase, beta (Upb1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Upb1 (Myc-DDK-tagged) - Mouse ureidopropionase, beta (Upb1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Upb1 (Myc-DDK-tagged) - Mouse ureidopropionase, beta (Upb1), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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