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UPB1 / BUP1 antibody

Principal name

UPB1 / BUP1 antibody

Alternative names for UPB1 / BUP1 antibody

BUP-1, Beta-ureidopropionase, Beta-alanine synthase, N-carbamoyl-beta-alanine amidohydrolase

SwissProt ID

Q03248 (Rat), Q8VC97 (Mouse), Q9UBR1 (Human)

Gene ID

51733 (UPB1), 103149 (Upb1)

Ncbi ID

9606, NP_057411, NP_057411.1, NM_133995, NP_598756.1

Available reactivities

Hu (Human), Arabidopsis, Ce (C. elegans), Can (Canine), Chk (Chicken), Dros (Drosophila), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Gt (Goat), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of UPB1 / BUP1 antibody

UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activityThis gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.

General readings

van (2004) Hum. Mol. Genet. 13 (22), 2793-2801

UPB1 monoclonal antibody (M09), clone 3F12. Western Blot analysis of UPB1 expression in human liver.

H00051733-M09

UPB1 monoclonal antibody (M09), clone 3F12. Western Blot analysis of UPB1 expression in Jurkat ( Cat # L017V1 ).

H00051733-M09

Human Jurkat; WB Suggested Anti-UPB1 Antibody Titration: 2.5ug/ml. Positive Control: Jurkat cell lysate; UPB1 antibody - middle region (ARP42467_T100) in Human Jurkat cells using Western Blot

ARP42467_T100

Human PANC1; WB Suggested Anti-UPB1 Antibody Titration: 0.2-1 ug/ml. Positive Control: PANC1 cell lysate. UPB1 is supported by BioGPS gene expression data to be expressed in PANC1.; UPB1 antibody - middle region (ARP42468_P050) in Human PANC1 cells using Western Blot

ARP42468_P050

TP323365

TP720186

TP760830

WB Suggested Anti-UPB1 Antibody Titration: 2.5 ug/ml; Positive Control: Jurkat cell lysate

TA344127

WB Suggested Anti-UPB1 Antibody Titration: 0.2-1 ug/ml; Positive Control: PANC1 cell lysate; UPB1 is supported by BioGPS gene expression data to be expressed in PANC1

TA344128

Primary Antibodies

Catalog No.	Host	Iso.	Pres.	React.	Applications
TA344127	UPB1 / BUP1 antibody
	Rabbit Polyclonal Anti-UPB1 Antibody
	Rabbit	IgG	Purified	Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt, Ze	WB	0.1 ml / €300.00
						OriGene Technologies, Inc.
TA344128	UPB1 / BUP1 antibody
	Rabbit Polyclonal Anti-UPB1 Antibody
	Rabbit	IgG	Purified	Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze	WB	0.1 ml / €360.00
						OriGene Technologies, Inc.

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