UPF1 / RENT1 antibody

Principal name

UPF1 / RENT1 antibody

Alternative names for UPF1 / RENT1 antibody

NORF1, KIAA0221, Up-frameshift suppressor 1 homolog, Regulator of nonsense transcripts 1, ATP-dependent helicase RENT1, Nonsense mRNA reducing factor 1

SwissProt ID

Q92900 (Human), Q9EPU0 (Mouse)

Gene ID

5976 (UPF1), 19704 (Upf1)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Ze (Zebrafish), African clawed frog, Rt (Rat), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of UPF1 / RENT1 antibody

UPF1 is a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. UPF1 is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Ajamian,L., (2008) RNA 14 (5), 914-927

14 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

UPF1 / RENT1 antibody

  UPF1 Rabbit Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using UPF1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

UPF1 / RENT1 antibody

  Rabbit Polyclonal Anti-UPF1 Antibody  
WB Suggested Anti-UPF1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Transfected 293T Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

UPF1 / RENT1 (N-term) antibody

Western blot analysis of RENT1 (arrow) using rabbit polyclonal RENT1 Antibody (N-term) (AP11687PU-N). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the RENT1 gene (Lane 2) (Origene Technologies). Rabbit Ig Purified Hu, Ms
0.4 ml / €370.00
  Acris Antibodies GmbH

UPF1 / RENT1 antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using UPF1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
50 µg / €230.00
  Assay Biotech

UPF1 / RENT1 antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using UPF1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

UPF1 - human gene knockout kit via CRISPR

UPF1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

UPF1 - human gene knockout kit via CRISPR

UPF1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

UPF1 - human gene knockout kit via CRISPR

UPF1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

UPF1 - human gene knockout kit via CRISPR

UPF1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Upf1 - mouse gene knockout kit via CRISPR

Upf1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Upf1 - mouse gene knockout kit via CRISPR

Upf1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Upf1 - mouse gene knockout kit via CRISPR

Upf1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Upf1 - mouse gene knockout kit via CRISPR

Upf1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

UPF1 / RENT1

  Recombinant protein of human UPF1 regulator of nonsense transcripts homolog (yeast) (UPF1)  
UPF1 / RENT1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

14 Item(s)

per page
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